REVERSIBILITY OF LYMPHOMAS AND LYMPHOPROLIFERATIVE LESIONS DEVELOPING UNDER CYCLOSPORIN-STEROID THERAPY

T. E. Starzl; K. A. Porter; S. Iwatsuki; J. T. Rosenthal; B. W. Shaw; R. W. Atchison; M. A. Nalesnik; M. Ho; B. P. Griffith; T. R. Hakala; R. L. Hardesty; R. Jaffe; H. T. Bahnson

doi:10.1016/S0140-6736(84)90994-2

REVERSIBILITY OF LYMPHOMAS AND LYMPHOPROLIFERATIVE LESIONS DEVELOPING UNDER CYCLOSPORIN-STEROID THERAPY

T. E. Starzl, K. A. Porter, S. Iwatsuki, J. T. Rosenthal, B. W. Shaw, R. W. Atchison, M. A. Nalesnik, M. Ho, B. P. Griffith, T. R. Hakala, R. L. Hardesty, R. Jaffe, H. T. Bahnson

Transplant

Research output: Contribution to journal › Article

965 Scopus citations

Abstract

Post-transplant lymphomas or other lymphoproliferative lesions, which were usually associated with Epstein-Barr virus infections, developed in 8, 4, 3, and 2 recipients, respectively, of cadaveric kidney, liver, heart, and heart-lung homografts. Reduction or discontinuance of immunosuppression caused regression of the lesions, often without subsequent rejection of the grafts. Chemotherapy and irradiation were not valuable. The findings may influence policies about treating other kinds of post-transplantation neoplasms.

Original language	English (US)
Pages (from-to)	583-587
Number of pages	5
Journal	The Lancet
Volume	323
Issue number	8377
DOIs	https://doi.org/10.1016/S0140-6736(84)90994-2
State	Published - Mar 17 1984

ASJC Scopus subject areas

Medicine(all)

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Starzl, T. E., Porter, K. A., Iwatsuki, S., Rosenthal, J. T., Shaw, B. W., Atchison, R. W., Nalesnik, M. A., Ho, M., Griffith, B. P., Hakala, T. R., Hardesty, R. L., Jaffe, R., & Bahnson, H. T. (1984). REVERSIBILITY OF LYMPHOMAS AND LYMPHOPROLIFERATIVE LESIONS DEVELOPING UNDER CYCLOSPORIN-STEROID THERAPY. The Lancet, 323(8377), 583-587. https://doi.org/10.1016/S0140-6736(84)90994-2

REVERSIBILITY OF LYMPHOMAS AND LYMPHOPROLIFERATIVE LESIONS DEVELOPING UNDER CYCLOSPORIN-STEROID THERAPY. / Starzl, T. E.; Porter, K. A.; Iwatsuki, S.; Rosenthal, J. T.; Shaw, B. W.; Atchison, R. W.; Nalesnik, M. A.; Ho, M.; Griffith, B. P.; Hakala, T. R.; Hardesty, R. L.; Jaffe, R.; Bahnson, H. T.

In: The Lancet, Vol. 323, No. 8377, 17.03.1984, p. 583-587.

Research output: Contribution to journal › Article

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abstract = "Post-transplant lymphomas or other lymphoproliferative lesions, which were usually associated with Epstein-Barr virus infections, developed in 8, 4, 3, and 2 recipients, respectively, of cadaveric kidney, liver, heart, and heart-lung homografts. Reduction or discontinuance of immunosuppression caused regression of the lesions, often without subsequent rejection of the grafts. Chemotherapy and irradiation were not valuable. The findings may influence policies about treating other kinds of post-transplantation neoplasms.",

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