Ribavirin: Efficacy in the treatment of murine autoimmune disease

Lynell W. Klassen, Daniel R. Budman, Gary W. Williams, Alfred D. Steinberg, N. Lynn Gerber

Research output: Contribution to journalArticle

22 Scopus citations

Abstract

Ribavirin, a drug with known antiviral activity, was given to mice with established lupus nephritis. Ribavirin was effective in prolonging survival, reducing the titer of antibodies to DNA, and reversing proteinuria. Other antiviral agents were not effective in the dosages used.

Original languageEnglish (US)
Pages (from-to)787-789
Number of pages3
JournalScience
Volume195
Issue number4280
DOIs
StatePublished - Jan 1 1977

ASJC Scopus subject areas

  • General

Fingerprint Dive into the research topics of 'Ribavirin: Efficacy in the treatment of murine autoimmune disease'. Together they form a unique fingerprint.

  • Cite this

    Klassen, L. W., Budman, D. R., Williams, G. W., Steinberg, A. D., & Gerber, N. L. (1977). Ribavirin: Efficacy in the treatment of murine autoimmune disease. Science, 195(4280), 787-789. https://doi.org/10.1126/science.299957