Ribavirin: Efficacy in the treatment of murine autoimmune disease

Lynell W. Klassen, Daniel R. Budman, Gary W. Williams, Alfred D. Steinberg, N. Lynn Gerber

Research output: Contribution to journalArticlepeer-review

23 Scopus citations

Abstract

Ribavirin, a drug with known antiviral activity, was given to mice with established lupus nephritis. Ribavirin was effective in prolonging survival, reducing the titer of antibodies to DNA, and reversing proteinuria. Other antiviral agents were not effective in the dosages used.

Original languageEnglish (US)
Pages (from-to)787-789
Number of pages3
JournalScience
Volume195
Issue number4280
DOIs
StatePublished - 1977
Externally publishedYes

ASJC Scopus subject areas

  • General

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