TY - JOUR
T1 - Risk factors for chronic mastitis in morocco and Egypt
AU - Oltean, Hanna N.
AU - Soliman, Amr S.
AU - Omar, Omar S.
AU - Youssef, Tamer F.
AU - Karkouri, Mehdi
AU - Abdel-Aziz, Azza
AU - Hablas, Ahmad
AU - Blachley, Taylor
AU - Tahri, Ali
AU - Merajver, Sofia D.
N1 - Funding Information:
This workwas supported by the Italian MIUR, in the frame of the following projects: PRIN2010-11 'Dalle materie prime del sistema Terra alle applicazioni tecnologiche: studi cristallochimici e strutturali' (2010EARRRZ 008, local scientific responsible SQ) and FIRB, Futuro in Ricerca 'Impose Pressure and Change Technology' (RBFR12CLQD, local scientific responsible RA).
PY - 2013
Y1 - 2013
N2 - Chronic mastitis is a prolonged inflammatory breast disease, and little is known about its etiology. We identified 85 cases and 112 controls from 5 hospitals in Morocco and Egypt. Cases were women with chronic mastitis (including periductal, lobular, granulomatous, lymphocytic, and duct ectasia with mastitis). Controls had benign breast disease, including fibroadenoma, benign phyllodes, and adenosis. Both groups were identified from histopathologically diagnosed patients from 2008 to 2011, frequency-matched on age. Patient interviews elicited demographic, reproductive, breastfeeding, and clinical histories. Cases had higher parity than controls (OR = 1.75, 1.62-1.90) and more reported history of contraception use (OR = 2.73, 2.07-3.61). Cases were less likely to report wearing a bra (OR = 0.56, 0.47-0.67) and less often used both breasts for breastfeeding (OR = 4.40, 3.39-5.72). Chronic mastitis cases were significantly less likely to be employed outside home (OR = 0.71, 0.60-0.84) and more likely to report mice in their households (OR = 1.63, 1.36-1.97). This is the largest case-control study reported to date on risk factors for chronic mastitis. Our study highlights distinct reproductive risk factors for the disease. Future studies should further explore these factors and the possible immunological and susceptibility predisposing conditions.
AB - Chronic mastitis is a prolonged inflammatory breast disease, and little is known about its etiology. We identified 85 cases and 112 controls from 5 hospitals in Morocco and Egypt. Cases were women with chronic mastitis (including periductal, lobular, granulomatous, lymphocytic, and duct ectasia with mastitis). Controls had benign breast disease, including fibroadenoma, benign phyllodes, and adenosis. Both groups were identified from histopathologically diagnosed patients from 2008 to 2011, frequency-matched on age. Patient interviews elicited demographic, reproductive, breastfeeding, and clinical histories. Cases had higher parity than controls (OR = 1.75, 1.62-1.90) and more reported history of contraception use (OR = 2.73, 2.07-3.61). Cases were less likely to report wearing a bra (OR = 0.56, 0.47-0.67) and less often used both breasts for breastfeeding (OR = 4.40, 3.39-5.72). Chronic mastitis cases were significantly less likely to be employed outside home (OR = 0.71, 0.60-0.84) and more likely to report mice in their households (OR = 1.63, 1.36-1.97). This is the largest case-control study reported to date on risk factors for chronic mastitis. Our study highlights distinct reproductive risk factors for the disease. Future studies should further explore these factors and the possible immunological and susceptibility predisposing conditions.
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U2 - 10.1155/2013/184921
DO - 10.1155/2013/184921
M3 - Article
C2 - 24327928
AN - SCOPUS:84890045678
SN - 2090-8040
VL - 2013
JO - International Journal of Inflammation
JF - International Journal of Inflammation
M1 - 184921
ER -