TY - JOUR
T1 - Role of invasive functional assessment in surgical revascularization of coronary artery disease
AU - Baibhav, Bipul
AU - Gedela, Maheedhar
AU - Moulton, Michael
AU - Pavlides, Gregory
AU - Pompili, Vincent
AU - Rab, Tanveer
AU - Dangas, George
AU - Bhatt, Deepak L.
AU - Siddique, Aleem
AU - Chatzizisis, Yiannis S.
N1 - Publisher Copyright:
© 2018 American Heart Association, Inc.
PY - 2018
Y1 - 2018
N2 - In patients with stable coronary artery disease, percutaneous coronary intervention is associated with improved outcomes if the lesion is deemed significant by invasive functional assessment using fractional flow reserve. Recent studies have shown that a revascularization strategy using instantaneous wave-free ratio is noninferior to fractional flow reserve in patients with intermediate-grade stenoses. The decision to perform coronary artery bypass grafting surgery is usually based on anatomic assessment of stenosis severity by coronary angiography. The data on the role of invasive functional assessment in guiding surgical revascularization are limited. In this review, we discuss the diagnostic and prognostic significance of invasive functional assessment in patients considered for coronary artery bypass grafting. In addition, we critically discuss ongoing and future clinical trials on the role of invasive functional assessment in surgical revascularization.
AB - In patients with stable coronary artery disease, percutaneous coronary intervention is associated with improved outcomes if the lesion is deemed significant by invasive functional assessment using fractional flow reserve. Recent studies have shown that a revascularization strategy using instantaneous wave-free ratio is noninferior to fractional flow reserve in patients with intermediate-grade stenoses. The decision to perform coronary artery bypass grafting surgery is usually based on anatomic assessment of stenosis severity by coronary angiography. The data on the role of invasive functional assessment in guiding surgical revascularization are limited. In this review, we discuss the diagnostic and prognostic significance of invasive functional assessment in patients considered for coronary artery bypass grafting. In addition, we critically discuss ongoing and future clinical trials on the role of invasive functional assessment in surgical revascularization.
KW - Coronary angiography
KW - Coronary artery bypass
KW - Coronary artery disease
KW - Fractional flow reserve
KW - Percutaneous coronary revascularization
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U2 - 10.1161/CIRCULATIONAHA.117.031182
DO - 10.1161/CIRCULATIONAHA.117.031182
M3 - Article
C2 - 29661951
AN - SCOPUS:85053796345
SN - 0009-7322
VL - 137
SP - 1731
EP - 1739
JO - Circulation
JF - Circulation
IS - 16
ER -