Role of non-Genetic Risk Factors in Exacerbating Alcohol-related organ damage

Natalia A. Osna; Rakesh Bhatia; Christopher Thompson; Surinder K. Batra; Sushil Kumar; Yeonhee Cho; Gyongyi Szabo; Patricia E. Molina; Steven A. Weinman; Murali Ganesan; Kusum K. Kharbanda

doi:10.1016/j.alcohol.2020.05.002

Role of non-Genetic Risk Factors in Exacerbating Alcohol-related organ damage

Natalia A. Osna, Rakesh Bhatia, Christopher Thompson, Surinder K. Batra, Sushil Kumar, Yeonhee Cho, Gyongyi Szabo, Patricia E. Molina, Steven A. Weinman, Murali Ganesan, Kusum K. Kharbanda

Research output: Contribution to journal › Review article › peer-review

Abstract

This review provides a summary of the symposium titled “Role of Non-Genetic Risk Factors in Exacerbating Alcohol-Related Organ Damage”, which was held at the 42nd Annual Meeting of the Research Society on Alcoholism. The goals of the symposium were to provide newer insights into the role of non-genetic factors, including specific external factors, notably infectious agents or lifestyle factors, that synergistically act to exacerbate alcohol pathogenicity to generate more dramatic downstream biological defects. This summary of the symposium will benefit junior/senior basic scientists and clinicians currently investigating/treating alcohol-induced organ pathology, as well as undergraduate, graduate, and post-graduate students and fellows.

Original language	English (US)
Pages (from-to)	63-72
Number of pages	10
Journal	Alcohol
Volume	87
DOIs	https://doi.org/10.1016/j.alcohol.2020.05.002
State	Published - Sep 2020

Keywords

HBV
HIV
alcohol
infectious agents
neutrophil extracellular traps
smoking

ASJC Scopus subject areas

Health(social science)
Biochemistry
Toxicology
Neurology
Behavioral Neuroscience

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Role of non-Genetic Risk Factors in Exacerbating Alcohol-related organ damage. / Osna, Natalia A.; Bhatia, Rakesh; Thompson, Christopher; Batra, Surinder K.; Kumar, Sushil; Cho, Yeonhee; Szabo, Gyongyi; Molina, Patricia E.; Weinman, Steven A.; Ganesan, Murali; Kharbanda, Kusum K.

In: Alcohol, Vol. 87, 09.2020, p. 63-72.

Research output: Contribution to journal › Review article › peer-review

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title = "Role of non-Genetic Risk Factors in Exacerbating Alcohol-related organ damage",

abstract = "This review provides a summary of the symposium titled “Role of Non-Genetic Risk Factors in Exacerbating Alcohol-Related Organ Damage”, which was held at the 42nd Annual Meeting of the Research Society on Alcoholism. The goals of the symposium were to provide newer insights into the role of non-genetic factors, including specific external factors, notably infectious agents or lifestyle factors, that synergistically act to exacerbate alcohol pathogenicity to generate more dramatic downstream biological defects. This summary of the symposium will benefit junior/senior basic scientists and clinicians currently investigating/treating alcohol-induced organ pathology, as well as undergraduate, graduate, and post-graduate students and fellows.",

keywords = "HBV, HIV, alcohol, infectious agents, neutrophil extracellular traps, smoking",

author = "Osna, {Natalia A.} and Rakesh Bhatia and Christopher Thompson and Batra, {Surinder K.} and Sushil Kumar and Yeonhee Cho and Gyongyi Szabo and Molina, {Patricia E.} and Weinman, {Steven A.} and Murali Ganesan and Kharbanda, {Kusum K.}",

note = "Funding Information: The research reported here in this summary and presented at the RSA annual meeting was supported by Merit Review grants, BX004053 (KKK) from the United States Department of Veterans Affairs and the National Institutes of Health under award numbers R21 AA026428 (SK, KKK), R01 AA026723 (KKK), K01 AA026864 (MG), R01 AA027189 (NAO), R01 AA015576 (GS), R01 AA017729 (GS), R01 CA228524 (SKB), R01 AA12863 (SW), P01 CA217798 (SKB), P60 AA009803 (PM), UH2 AA026198 (PM) and UH2 AA026226 (PM). ",

year = "2020",

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doi = "10.1016/j.alcohol.2020.05.002",

language = "English (US)",

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AU - Osna, Natalia A.

AU - Bhatia, Rakesh

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AU - Kumar, Sushil

AU - Cho, Yeonhee

AU - Szabo, Gyongyi

AU - Molina, Patricia E.

AU - Weinman, Steven A.

AU - Ganesan, Murali

AU - Kharbanda, Kusum K.

N1 - Funding Information: The research reported here in this summary and presented at the RSA annual meeting was supported by Merit Review grants, BX004053 (KKK) from the United States Department of Veterans Affairs and the National Institutes of Health under award numbers R21 AA026428 (SK, KKK), R01 AA026723 (KKK), K01 AA026864 (MG), R01 AA027189 (NAO), R01 AA015576 (GS), R01 AA017729 (GS), R01 CA228524 (SKB), R01 AA12863 (SW), P01 CA217798 (SKB), P60 AA009803 (PM), UH2 AA026198 (PM) and UH2 AA026226 (PM).

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AB - This review provides a summary of the symposium titled “Role of Non-Genetic Risk Factors in Exacerbating Alcohol-Related Organ Damage”, which was held at the 42nd Annual Meeting of the Research Society on Alcoholism. The goals of the symposium were to provide newer insights into the role of non-genetic factors, including specific external factors, notably infectious agents or lifestyle factors, that synergistically act to exacerbate alcohol pathogenicity to generate more dramatic downstream biological defects. This summary of the symposium will benefit junior/senior basic scientists and clinicians currently investigating/treating alcohol-induced organ pathology, as well as undergraduate, graduate, and post-graduate students and fellows.

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KW - HIV

KW - alcohol

KW - infectious agents

KW - neutrophil extracellular traps

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JO - Alcohol

JF - Alcohol

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ER -

Role of non-Genetic Risk Factors in Exacerbating Alcohol-related organ damage

Abstract

Keywords

ASJC Scopus subject areas

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