Abstract
Dietary administration of sodium saccharin to male Fischer rats increased the rate of DNA synthesis of the urinary bladder epithelium as measured by tritiated thymidine uptake. A multifocal mild epithelial hyperplasia was induced, which was most readily detected by scanning electron microscopy, with pleomorphic microvilli present on many of the hyperplastic cells.
Original language | English (US) |
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Pages (from-to) | 734-736 |
Number of pages | 3 |
Journal | Cancer Research |
Volume | 40 |
Issue number | 3 |
State | Published - Mar 1 1980 |
Externally published | Yes |
ASJC Scopus subject areas
- Oncology
- Cancer Research