SCLERODERMATOUS GRAFT-VERSUS-HOST DISEASE LIMITED TO AN AREA OF MEASLES EXANTHEM

John R. Fenyk, Phyllis I. Warkentin, Robert W. Goltz, Mark E. Nesbit, Peter F. Coccia, Clark M. Smith, William Krivit, John E. Neely, Norma K.C. Ramsay, John H. Kersey

Research output: Contribution to journalArticle

40 Scopus citations

Abstract

A female patient with severe idiopathic aplastic anæmia received a successful bone-marrow transplant from her HLA-identical, mixed-lymphocyte-culture-compatible, brother. 8 months after transplantation she had localised cutaneous measles. Chronic sclerodermatous changes developed which were indistinguishable from chronic graft-versus-host disease and were limited to the areas of the original exanthem. Interaction between viral infection and minor histocompatibility differences probably resulted in graft-versus-host disease in this patient.

Original languageEnglish (US)
Pages (from-to)472-473
Number of pages2
JournalThe Lancet
Volume311
Issue number8062
DOIs
StatePublished - Mar 4 1978

ASJC Scopus subject areas

  • Medicine(all)

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    Fenyk, J. R., Warkentin, P. I., Goltz, R. W., Nesbit, M. E., Coccia, P. F., Smith, C. M., Krivit, W., Neely, J. E., Ramsay, N. K. C., & Kersey, J. H. (1978). SCLERODERMATOUS GRAFT-VERSUS-HOST DISEASE LIMITED TO AN AREA OF MEASLES EXANTHEM. The Lancet, 311(8062), 472-473. https://doi.org/10.1016/S0140-6736(78)90136-8