TY - JOUR
T1 - Sclerosing inflammatory pseudotumor of the eye
AU - Uy, Harvey S.
AU - Nguyen, Quan Dong
AU - Arbour, Jean
AU - Gravel, Michel
AU - D'Amico, Donald J.
AU - Jakobiec, Frederick A.
AU - Foster, C. Stephen
PY - 2001
Y1 - 2001
N2 - We report the clinical course and pathologic findings in a case of intraocular sclerosing inflammatory pseudotumor in a 21-year-old man. The patient initially had a unilateral right interstitial keratitis, scleritis, uveitis, ciliary body mass, and retinal detachment. Scleral and vitreous biopsy specimens revealed an inflammatory process. The eye was eventually enucleated despite therapy with high doses of prednisone and ciprofloxacin hydrochloride. Histologic examination of the globe showed nongranulomatous, acute (neutrophils) and chronic (lymphocytes and histiocytes) inflammation with proliferation of fibrous tissue within the vitreous cavity, uvea, sclera, and contiguous orbital fibroadipose tissue. The contralateral eye later developed a similar mass that resolved following aggressive and prolonged immunosuppressive therapy with retention of 20/16 visual acuity.
AB - We report the clinical course and pathologic findings in a case of intraocular sclerosing inflammatory pseudotumor in a 21-year-old man. The patient initially had a unilateral right interstitial keratitis, scleritis, uveitis, ciliary body mass, and retinal detachment. Scleral and vitreous biopsy specimens revealed an inflammatory process. The eye was eventually enucleated despite therapy with high doses of prednisone and ciprofloxacin hydrochloride. Histologic examination of the globe showed nongranulomatous, acute (neutrophils) and chronic (lymphocytes and histiocytes) inflammation with proliferation of fibrous tissue within the vitreous cavity, uvea, sclera, and contiguous orbital fibroadipose tissue. The contralateral eye later developed a similar mass that resolved following aggressive and prolonged immunosuppressive therapy with retention of 20/16 visual acuity.
UR - http://www.scopus.com/inward/record.url?scp=0035069639&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0035069639&partnerID=8YFLogxK
U2 - 10.1001/archopht.119.4.603
DO - 10.1001/archopht.119.4.603
M3 - Article
C2 - 11296029
AN - SCOPUS:0035069639
SN - 0003-9950
VL - 119
SP - 603
EP - 607
JO - Archives of Ophthalmology
JF - Archives of Ophthalmology
IS - 4
ER -