Searching for significance in TCR-cytoskeleton interactions

Steve Caplan, Michal Baniyash

Research output: Contribution to journalComment/debate

27 Scopus citations

Abstract

Two T-cell receptor (TCR) populations are expressed on T cells; one is linked to the cytoskeleton via its ζ chain. These cytoskeleton-linked receptors (30-40% of the total number of TCRs) might be important in TCR-mediated signaling and/or concurrent events. Here, differences between the two populations are summarized, and new data are examined to speculate on the functional significance of cytoskeleton-linked TCRs.

Original languageEnglish (US)
Pages (from-to)223-228
Number of pages6
JournalImmunology Today
Volume21
Issue number5
DOIs
StatePublished - 2000

ASJC Scopus subject areas

  • Immunology

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