Searching for smart durable coatings to promote bone marrow stromal cell growth while preventing biofilm formation

Fereydoon Namavar, John D. Jackson, J. Graham Sharp, Ethan E. Mann, Kenneth Bayles, Chin Li Cheung Barry, Connie A. Feschuk, Shailaja Varma, Hani Haider, Kevin L. Garvin

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Scopus citations

Abstract

There is a great need to develop methods to regulate cellular growth in order to enhance or prevent cell proliferation, as needed, to either improve health or prevent disease. In this work we evaluated the adhesion, survival and growth of bone marrow stromal cells on the surface of several new ion beam engineered nano-crystals of ceramic hard coatings such as zirconium, titanium, tantalum and cerium oxides. Cell adhesion and growth on the ceramic coatings were compared to adhesion and growth on a nano-crystalline silver coating which is known to possess antibacterial properties. The initial results of a study to determine the effect of nanocrystalline titanium and silver coating on staphylococcus aureus biofilm growth is also discussed.

Original languageEnglish (US)
Title of host publicationBiofilm-Material Interactions
Subtitle of host publicationNew Tools, Technologies and Opportunities
PublisherMaterials Research Society
Pages1-7
Number of pages7
ISBN (Print)9781604234107
DOIs
StatePublished - 2006
Event2006 MRS Fall Meeting - Boston, MA, United States
Duration: Nov 27 2006Dec 1 2006

Publication series

NameMaterials Research Society Symposium Proceedings
Volume954
ISSN (Print)0272-9172

Conference

Conference2006 MRS Fall Meeting
Country/TerritoryUnited States
CityBoston, MA
Period11/27/0612/1/06

ASJC Scopus subject areas

  • General Materials Science
  • Condensed Matter Physics
  • Mechanics of Materials
  • Mechanical Engineering

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