Self-assembly/disassembly of giant double-hydrophilic polymersomes at biologically-relevant pH

Sun Hae Ra Shin, Patrick T. McAninch, Ian M. Henderson, Andrew Gomez, Adrienne C. Greene, Eric C. Carnes, Walter F. Paxton

Research output: Contribution to journalArticlepeer-review

19 Scopus citations


Self-assembled giant polymer vesicles prepared from double-hydrophilic diblock copolymers, poly(ethylene oxide)-b-poly(acrylic acid) (PEO-PAA) show significant degradation in response to pH changes. Because of the switching behavior of the diblock copolymers at biologically-relevant pH environments (2 to 9), these polymer vesicles have potential biomedical applications as smart delivery vehicles.

Original languageEnglish (US)
Pages (from-to)9043-9046
Number of pages4
JournalChemical Communications
Issue number65
StatePublished - 2018

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • General Chemistry
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry


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