Self-assembly/disassembly of giant double-hydrophilic polymersomes at biologically-relevant pH

Sun Hae Ra Shin; Patrick T. McAninch; Ian M. Henderson; Andrew Gomez; Adrienne C. Greene; Eric C. Carnes; Walter F. Paxton

doi:10.1039/c8cc05155k

Self-assembly/disassembly of giant double-hydrophilic polymersomes at biologically-relevant pH

Sun Hae Ra Shin, Patrick T. McAninch, Ian M. Henderson, Andrew Gomez, Adrienne C. Greene, Eric C. Carnes, Walter F. Paxton

Environmental, Agricultural & Occupational Health Sciences

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

Abstract

Self-assembled giant polymer vesicles prepared from double-hydrophilic diblock copolymers, poly(ethylene oxide)-b-poly(acrylic acid) (PEO-PAA) show significant degradation in response to pH changes. Because of the switching behavior of the diblock copolymers at biologically-relevant pH environments (2 to 9), these polymer vesicles have potential biomedical applications as smart delivery vehicles.

Original language	English (US)
Pages (from-to)	9043-9046
Number of pages	4
Journal	Chemical Communications
Volume	54
Issue number	65
DOIs	https://doi.org/10.1039/c8cc05155k
State	Published - 2018

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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abstract = "Self-assembled giant polymer vesicles prepared from double-hydrophilic diblock copolymers, poly(ethylene oxide)-b-poly(acrylic acid) (PEO-PAA) show significant degradation in response to pH changes. Because of the switching behavior of the diblock copolymers at biologically-relevant pH environments (2 to 9), these polymer vesicles have potential biomedical applications as smart delivery vehicles.",

author = "Shin, {Sun Hae Ra} and McAninch, {Patrick T.} and Henderson, {Ian M.} and Andrew Gomez and Greene, {Adrienne C.} and Carnes, {Eric C.} and Paxton, {Walter F.}",

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AU - Shin, Sun Hae Ra

AU - McAninch, Patrick T.

AU - Henderson, Ian M.

AU - Gomez, Andrew

AU - Greene, Adrienne C.

AU - Carnes, Eric C.

AU - Paxton, Walter F.

N1 - Publisher Copyright: © The Royal Society of Chemistry.

PY - 2018

Y1 - 2018

N2 - Self-assembled giant polymer vesicles prepared from double-hydrophilic diblock copolymers, poly(ethylene oxide)-b-poly(acrylic acid) (PEO-PAA) show significant degradation in response to pH changes. Because of the switching behavior of the diblock copolymers at biologically-relevant pH environments (2 to 9), these polymer vesicles have potential biomedical applications as smart delivery vehicles.

AB - Self-assembled giant polymer vesicles prepared from double-hydrophilic diblock copolymers, poly(ethylene oxide)-b-poly(acrylic acid) (PEO-PAA) show significant degradation in response to pH changes. Because of the switching behavior of the diblock copolymers at biologically-relevant pH environments (2 to 9), these polymer vesicles have potential biomedical applications as smart delivery vehicles.

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Self-assembly/disassembly of giant double-hydrophilic polymersomes at biologically-relevant pH

Abstract

ASJC Scopus subject areas

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