Sense and the science of childhood immunization: Can we achieve more with less?

Stephen K. Obaro, Martin O. Ota

Research output: Contribution to journalReview articlepeer-review

5 Scopus citations


The threat of biological terrorism with small pox virus and a global influenza pandemic in the face of limited vaccine supply recently stimulated research into the evaluation of fractional dose vaccine regimens, with promising immunogenicity results. While this approach is not new, it has been less applied to vaccines for less sensational but nevertheless, significant killer diseases. This manuscript provides an overview of the basics of immunization as it applies to the current practice of immunization in children, comments on the untapped avenues for cost reduction of vaccine delivery, and the potential for saving more lives with currently available resources.

Original languageEnglish (US)
Pages (from-to)6460-6467
Number of pages8
Issue number42-43
StatePublished - Oct 30 2006
Externally publishedYes


  • Cost-reduction
  • Dose
  • Reduced antigen
  • Vaccine

ASJC Scopus subject areas

  • Molecular Medicine
  • General Immunology and Microbiology
  • General Veterinary
  • Public Health, Environmental and Occupational Health
  • Infectious Diseases


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