Septum formation in aspergillus nidulans

Steven D. Harris

Research output: Contribution to journalReview articlepeer-review

69 Scopus citations


Filamentous fungi form multicellular hyphae that are partitioned by septa. In A. nidulans, septum formation requires the assembly of a septal band following the completion of mitosis. Recent observations show that this band is a dynamic structure composed of actin, a septin and a formin. In addition, assembly is dependent upon a conserved protein kinase cascade that regulates mitotic exit and septation in yeast. Hyphal differentiation may reflect the regulation of this cascade by cyclin-dependent kinase activity. In this review, the dynamics and regulation underlying the assembly of the septal band are discussed.

Original languageEnglish (US)
Pages (from-to)736-739
Number of pages4
JournalCurrent Opinion in Microbiology
Issue number6
StatePublished - 2001

ASJC Scopus subject areas

  • Microbiology
  • Microbiology (medical)
  • Infectious Diseases


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