Serial transverse enteroplasty allows children with short bowel to wean from parenteral nutrition

David F. Mercer, Brandy D. Hobson, Brandi K. Gerhardt, Wendy J. Grant, Luciano M. Vargas, Alan N. Langnas, Ruben E. Quiros-Tejeira

Research output: Contribution to journalArticlepeer-review

42 Scopus citations


Objective To analyze the effects of serial transverse enteroplasty (STEP) on parenteral and enteral calories in children with short bowel syndrome, and examine short- and long-term complications. Study design A retrospective analysis of prospectively-collected data from a large single center cohort of patients undergoing STEP procedure was analyzed. Baseline demographic and clinical information, operative data, and short- and long-term complications were recorded. Detailed growth and nutritional data were obtained for 6 months prior and 12 months following STEP procedure. Results Sixty-eight procedures were performed in 51 patients over a 68-month period. Median bowel length at first STEP was 51 cm with a median length gain of 54%. Repeat STEP patients had longer initial length (77 cm) and reduced length gain (20%). Operative times and blood loss were low, with few complications. Parenteral calorie requirement was stable or rising for 6 months prior to STEP, but decreased to median <20 kCal/kg/d at 1 year postop. Longer length gains were associated with higher risk of stricture formation. Seven children were transplanted, and 60% of nontransplanted children were enterally independent, with the remainder making ongoing progress; 48/51 children are alive at a median of 39 months follow-up. Conclusions STEP is shown to be safe, well tolerated, and to have definitive benefit in reducing parenteral calorie requirements over the first year following the procedure. It has an important role in achieving enteral independence in children with short bowel syndrome.

Original languageEnglish (US)
Pages (from-to)93-98
Number of pages6
JournalJournal of Pediatrics
Issue number1
StatePublished - Jan 2014

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


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