SERUM LEVELS OF GAMMA-AMINOBUTYRIC-ACID-LIKE ACTIVITY IN ACUTE AND CHRONIC HEPATOCELLULAR DISEASE

P. Ferenci; G. Kleinberger; D. F. Schafer; J. H. Hoofnagle; E. A. Jones

doi:10.1016/S0140-6736(83)90735-3

SERUM LEVELS OF GAMMA-AMINOBUTYRIC-ACID-LIKE ACTIVITY IN ACUTE AND CHRONIC HEPATOCELLULAR DISEASE

P. Ferenci, G. Kleinberger, D. F. Schafer, J. H. Hoofnagle, E. A. Jones

Research output: Contribution to journal › Article

83 Scopus citations

Abstract

Serum levels of GABA (gamma-aminobutyric acid)-like activity were measured by a radioreceptor assay in 22 healthy subjects and 170 patients with liver diseases. Levels were within normal limits (mean±SEM in healthy controls 0 ·52±0·04 μmol/l; range 0·2-0·8 μmol/l GABA equivalents) in most patients with uncomplicated acute viral hepatitis, compensated chronic hepatitis, and primary biliary cirrhosis (PBC). In 96% of patients with compensated (non-PBC) cirrhosis levels were slightly high (1·5+0·06 μmol/l). In 4 patients with.

Original language	English (US)
Pages (from-to)	811-814
Number of pages	4
Journal	The Lancet
Volume	322
Issue number	8354
DOIs	https://doi.org/10.1016/S0140-6736(83)90735-3
State	Published - Oct 8 1983

ASJC Scopus subject areas

Medicine(all)

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Ferenci, P., Kleinberger, G., Schafer, D. F., Hoofnagle, J. H., & Jones, E. A. (1983). SERUM LEVELS OF GAMMA-AMINOBUTYRIC-ACID-LIKE ACTIVITY IN ACUTE AND CHRONIC HEPATOCELLULAR DISEASE. The Lancet, 322(8354), 811-814. https://doi.org/10.1016/S0140-6736(83)90735-3

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