TY - JOUR
T1 - Sesame as an allergen in Lebanese food products
T2 - Occurrence, consumption and quantitative risk assessment
AU - Touma, Joseph
AU - Dominguez, Silvia
AU - La Vieille, Sébastien
AU - Remington, Benjamin C.
AU - Baumert, Joseph L.
AU - Théolier, Jérémie
AU - Godefroy, Samuel Benrejeb
N1 - Funding Information:
This work was supported through funding from the Food Regulatory Platform Fund, part of the Trust fund of Laval University , and specifically through contributions and donations provided by R-biopharm inc. to the trust fund. The author would like to thank Dr Michel Afram (Director general of the Lebanese Agriculture Research Institute) for his support.
Funding Information:
This work was supported through funding from the Food Regulatory Platform Fund, part of the Trust fund of Laval University, and specifically through contributions and donations provided by R-biopharm inc. to the trust fund. The author would like to thank Dr Michel Afram (Director general of the Lebanese Agriculture Research Institute) for his support.
Publisher Copyright:
© 2021 Elsevier Ltd
PY - 2021/10
Y1 - 2021/10
N2 - Despite the intensive use of sesame in the Middle Eastern diet, studies on this allergen in this region are lacking. A survey on the occurrence of sesame in Lebanese food products that did not contain this allergen as an ingredient, a food consumption survey conducted in Beirut schools, and the most recent sesame eliciting dose estimates were used to build a probabilistic risk assessment model providing estimates of sesame-induced allergic reactions per eating occasion and per week in Lebanese children and adolescents. Of 1270 food samples analysed, 34% contained sesame proteins (0.44–3392 mg kg−1). Sesame was detected in 47% of unlabeled bulk samples, 43% of samples with PAL, and 27% of samples without PAL. “Sfouf” had the highest concentration of sesame proteins (mean 549 mg kg−1), highest mean exposure per eating occasion (78 mg sesame proteins for children and 103 mg sesame proteins for adolescents), and posed the highest predicted risk per eating occasion (>20%) and per week (>13% individuals predicted in simulation experience at least 1 reaction). Bakery products (notably “sfouf”) may pose a serious risk to sesame-allergic children and adolescents in Lebanon. Enhanced guidance on the use of PAL is needed to better protect allergic consumers.
AB - Despite the intensive use of sesame in the Middle Eastern diet, studies on this allergen in this region are lacking. A survey on the occurrence of sesame in Lebanese food products that did not contain this allergen as an ingredient, a food consumption survey conducted in Beirut schools, and the most recent sesame eliciting dose estimates were used to build a probabilistic risk assessment model providing estimates of sesame-induced allergic reactions per eating occasion and per week in Lebanese children and adolescents. Of 1270 food samples analysed, 34% contained sesame proteins (0.44–3392 mg kg−1). Sesame was detected in 47% of unlabeled bulk samples, 43% of samples with PAL, and 27% of samples without PAL. “Sfouf” had the highest concentration of sesame proteins (mean 549 mg kg−1), highest mean exposure per eating occasion (78 mg sesame proteins for children and 103 mg sesame proteins for adolescents), and posed the highest predicted risk per eating occasion (>20%) and per week (>13% individuals predicted in simulation experience at least 1 reaction). Bakery products (notably “sfouf”) may pose a serious risk to sesame-allergic children and adolescents in Lebanon. Enhanced guidance on the use of PAL is needed to better protect allergic consumers.
KW - Eliciting dose
KW - Food allergen
KW - Labeling
KW - Lebanon
KW - Probabilistic risk assessment
KW - Sesame
UR - http://www.scopus.com/inward/record.url?scp=85112422893&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85112422893&partnerID=8YFLogxK
U2 - 10.1016/j.fct.2021.112511
DO - 10.1016/j.fct.2021.112511
M3 - Article
C2 - 34391860
AN - SCOPUS:85112422893
SN - 0278-6915
VL - 156
JO - Food and Chemical Toxicology
JF - Food and Chemical Toxicology
M1 - 112511
ER -