Sex chromosome abnormalities in lung cancer patients

Bhavana J. Dave, Vicki L. Hopwood, Margaret R. Spitz, Sen Pathak

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


Chromosomal analyses of lymphocytes from lung cancer patients and normal subjects revealed that the X and the Y chromosomes have both structural and numerical abnormalities in higher frequency in patients compared to the controls. These abnormalities included chromatid/isochromatid breaks, translocations, ring formation, and selective nondisjunctions, resulting in multisomies of either the X or Y chromosomes. Possible significance of these genetic abnormalities are discussed in relation to lung cancer patients.

Original languageEnglish (US)
Pages (from-to)24-28
Number of pages5
JournalCancer genetics and cytogenetics
Issue number1
StatePublished - Mar 1996
Externally publishedYes

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Cancer Research


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