Abstract
Comparison of the gene-expression profiles between adults of Drosophila melanogaster and Drosophila simulans has uncovered the evolution of genes that exhibit sex-dependent regulation. Approximately half the genes showed differences in expression between the species, and among these, ∼83% involved a gain, loss, increase, decrease, or reversal of sex-biased expression. Most of the interspecific differences in messenger RNA abundance affect male-biased genes. Genes that differ in expression between the species showed functional clustering only if they were sex-biased. Our results suggest that sex-dependent selection may drive changes in expression of many of the most rapidly evolving genes in the Drosophila transcriptome.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1742-1745 |
| Number of pages | 4 |
| Journal | Science |
| Volume | 300 |
| Issue number | 5626 |
| DOIs | |
| State | Published - Jun 13 2003 |
ASJC Scopus subject areas
- General
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Ranz, J. M., Castillo-Davis, C. I., Meiklejohn, C. D., & Hartl, D. L. (2003). Sex-dependent gene expression and evolution of the Drosophila transcriptome. Science, 300(5626), 1742-1745. https://doi.org/10.1126/science.1085881