The handling of outdoor air (OA) consumes a large amount of energy. CO 2-based demand controlled ventilation (DCV) is an application used to reduce the system OA intake with varying occupancy density. Several DCV control logics for single zone variable air volume (VAV) systems have been developed and verified. However, these control logics cannot be applied in a multiple zone system, which is a typical VAV system. This study proposed a CO 2-based DCV control logic for a multiple-zone VAV system. The airflow simulation was completed to assess the performance of this DCV control logic. The results showed that this DCV control logic satisfies the ventilation requirement of ASHRAE Standard 62.1-2010 and reduces the energy consumption.