Single-dose oral lacosamide in refractory simple partial status epilepticus: Case report and review

Maximiliano A. Hawkes; Marcos Fernández Suárez; Gabriela Ugarnes; Carlos D'Giano

doi:10.1097/WNF.0b013e31829b21ba

Single-dose oral lacosamide in refractory simple partial status epilepticus: Case report and review

Maximiliano A. Hawkes, Marcos Fernández Suárez, Gabriela Ugarnes, Carlos D'Giano

Research output: Contribution to journal › Review article › peer-review

5 Scopus citations

Abstract

OBJECTIVES: This study aimed to present 2 patients with simple partial refractory status epilepticus (RSE) treated with a single oral lacosamide (LCM) dose and to review the literature on this topic. METHOD: A retrospective description of 2 patients with simple partial RSE treated with 300 mg of LCM per os (PO) and a literature review were done. RESULTS: Both patients responded to single-dose oral LCM treatment with seizure cessation after 30 minutes. CONCLUSIONS: This is the first report on successful treatment of simple partial RSE with a single-dose of LCM PO. Oral LCM might represent an option for treatment of patients presenting with simple partial RSE.

Original language	English (US)
Pages (from-to)	138-140
Number of pages	3
Journal	Clinical Neuropharmacology
Volume	36
Issue number	4
DOIs	https://doi.org/10.1097/WNF.0b013e31829b21ba
State	Published - Jul 2013
Externally published	Yes

Keywords

Focal status epilepticus
Lacosamide
Refractory status epilepticus
Simple partial status epilepticus

ASJC Scopus subject areas

Pharmacology
Clinical Neurology
Pharmacology (medical)

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10.1097/WNF.0b013e31829b21ba

Cite this

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title = "Single-dose oral lacosamide in refractory simple partial status epilepticus: Case report and review",

abstract = "OBJECTIVES: This study aimed to present 2 patients with simple partial refractory status epilepticus (RSE) treated with a single oral lacosamide (LCM) dose and to review the literature on this topic. METHOD: A retrospective description of 2 patients with simple partial RSE treated with 300 mg of LCM per os (PO) and a literature review were done. RESULTS: Both patients responded to single-dose oral LCM treatment with seizure cessation after 30 minutes. CONCLUSIONS: This is the first report on successful treatment of simple partial RSE with a single-dose of LCM PO. Oral LCM might represent an option for treatment of patients presenting with simple partial RSE.",

keywords = "Focal status epilepticus, Lacosamide, Refractory status epilepticus, Simple partial status epilepticus",

author = "Hawkes, {Maximiliano A.} and {Fern{\'a}ndez Su{\'a}rez}, Marcos and Gabriela Ugarnes and Carlos D'Giano",

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T2 - Case report and review

AU - Hawkes, Maximiliano A.

AU - Fernández Suárez, Marcos

AU - Ugarnes, Gabriela

AU - D'Giano, Carlos

PY - 2013/7

Y1 - 2013/7

N2 - OBJECTIVES: This study aimed to present 2 patients with simple partial refractory status epilepticus (RSE) treated with a single oral lacosamide (LCM) dose and to review the literature on this topic. METHOD: A retrospective description of 2 patients with simple partial RSE treated with 300 mg of LCM per os (PO) and a literature review were done. RESULTS: Both patients responded to single-dose oral LCM treatment with seizure cessation after 30 minutes. CONCLUSIONS: This is the first report on successful treatment of simple partial RSE with a single-dose of LCM PO. Oral LCM might represent an option for treatment of patients presenting with simple partial RSE.

AB - OBJECTIVES: This study aimed to present 2 patients with simple partial refractory status epilepticus (RSE) treated with a single oral lacosamide (LCM) dose and to review the literature on this topic. METHOD: A retrospective description of 2 patients with simple partial RSE treated with 300 mg of LCM per os (PO) and a literature review were done. RESULTS: Both patients responded to single-dose oral LCM treatment with seizure cessation after 30 minutes. CONCLUSIONS: This is the first report on successful treatment of simple partial RSE with a single-dose of LCM PO. Oral LCM might represent an option for treatment of patients presenting with simple partial RSE.

KW - Focal status epilepticus

KW - Lacosamide

KW - Refractory status epilepticus

KW - Simple partial status epilepticus

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Single-dose oral lacosamide in refractory simple partial status epilepticus: Case report and review

Abstract

Keywords

ASJC Scopus subject areas

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