Single-dose oral lacosamide in refractory simple partial status epilepticus: Case report and review

Maximiliano A. Hawkes, Marcos Fernández Suárez, Gabriela Ugarnes, Carlos D'Giano

Research output: Contribution to journalReview articlepeer-review

5 Scopus citations

Abstract

OBJECTIVES: This study aimed to present 2 patients with simple partial refractory status epilepticus (RSE) treated with a single oral lacosamide (LCM) dose and to review the literature on this topic. METHOD: A retrospective description of 2 patients with simple partial RSE treated with 300 mg of LCM per os (PO) and a literature review were done. RESULTS: Both patients responded to single-dose oral LCM treatment with seizure cessation after 30 minutes. CONCLUSIONS: This is the first report on successful treatment of simple partial RSE with a single-dose of LCM PO. Oral LCM might represent an option for treatment of patients presenting with simple partial RSE.

Original languageEnglish (US)
Pages (from-to)138-140
Number of pages3
JournalClinical Neuropharmacology
Volume36
Issue number4
DOIs
StatePublished - Jul 2013
Externally publishedYes

Keywords

  • Focal status epilepticus
  • Lacosamide
  • Refractory status epilepticus
  • Simple partial status epilepticus

ASJC Scopus subject areas

  • Pharmacology
  • Clinical Neurology
  • Pharmacology (medical)

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