Single muscle fiber adaptations with marathon training

Scott Trappe, Matthew Harber, Andrew Creer, Philip Gallagher, Dustin Slivka, Kiril Minchev, David Whitsett

Research output: Contribution to journalArticle

80 Scopus citations

Abstract

The purpose of this investigation was to characterize the effects of marathon training on single muscle fiber contractile function in a group of recreational runners. Muscle biopsies were obtained from the gastrocnemius muscle of seven individuals (22 ± 1 yr, 177 ± 3 cm, and 68 ± 2 kg) before, after 13 wk of run training, and after 3 wk of taper. Slow-twitch myosin heavy chain [(MHC) I] and fast-twitch (MHC IIa) muscle fibers were analyzed for size, strength (Po), speed (Vo), and power. The run training program led to the successful completion of a marathon (range 3 h 56 min to 5 h 35 min). Oxygen uptake during submaximal running and citrate synthase activity were improved (P < 0.05) with the training program. Muscle fiber size declined (P < 0.05) by ∼20% in both fiber types after training. Po was maintained in both fiber types with training and increased (P < 0.05) by 18% in the MHC IIa fibers after taper. This resulted in >60% increase (P < 0.05) in force per cross-sectional area in both fiber types. Fiber Vo increased (P < 0.05) by 28% in MHC I fibers with training and was unchanged in MHC IIa fibers. Peak power increased (P < 0.05) in MHC I and IIa fibers after training with a further increase (P < 0.05) in MHC IIa fiber power after taper. These data show that marathon training decreased slow-twitch and fast-twitch muscle fiber size but that it maintained or improved the functional profile of these fibers. A taper period before the marathon further improved the functional profile of the muscle, which was targeted to the fast-twitch muscle fibers.

Original languageEnglish (US)
Pages (from-to)721-727
Number of pages7
JournalJournal of Applied Physiology
Volume101
Issue number3
DOIs
StatePublished - 2006

Keywords

  • Contractile properties
  • Performance
  • Taper

ASJC Scopus subject areas

  • Physiology
  • Physiology (medical)

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    Trappe, S., Harber, M., Creer, A., Gallagher, P., Slivka, D., Minchev, K., & Whitsett, D. (2006). Single muscle fiber adaptations with marathon training. Journal of Applied Physiology, 101(3), 721-727. https://doi.org/10.1152/japplphysiol.01595.2005