Single vs 2-Stage Revision for the Treatment of Periprosthetic Joint Infection

Beau J. Kildow, Craig J. Della-Valle, Bryan D. Springer

Research output: Contribution to journalArticlepeer-review

49 Scopus citations


Periprosthetic joint infection (PJI) is one of the most devastating complications following total joint arthroplasty, accounting for a projected 10,000 revision surgeries per year by 2030. Chronic PJI is complicated by the presence of bacterial biofilm, requiring removal of components, thorough debridement, and administration of antibiotics for effective eradication. Chronic PJI is currently managed with single-stage or 2-stage revision surgery. To date, there are no randomized, prospective studies available evaluating eradication rates and functional outcomes between the 2 techniques. In this review, both treatment options are described with the most current literature to guide effective surgical decision-making that is cost-effective while decreasing patient morbidity.

Original languageEnglish (US)
Pages (from-to)S24-S30
JournalJournal of Arthroplasty
Issue number3
StatePublished - Mar 2020
Externally publishedYes


  • infection
  • periprosthetic joint infection
  • single-stage revision
  • treatment
  • two-stage revision

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine


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