Single vs 2-Stage Revision for the Treatment of Periprosthetic Joint Infection

Beau J. Kildow; Craig J. Della-Valle; Bryan D. Springer

doi:10.1016/j.arth.2019.10.051

Single vs 2-Stage Revision for the Treatment of Periprosthetic Joint Infection

Beau J. Kildow, Craig J. Della-Valle, Bryan D. Springer

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Periprosthetic joint infection (PJI) is one of the most devastating complications following total joint arthroplasty, accounting for a projected 10,000 revision surgeries per year by 2030. Chronic PJI is complicated by the presence of bacterial biofilm, requiring removal of components, thorough debridement, and administration of antibiotics for effective eradication. Chronic PJI is currently managed with single-stage or 2-stage revision surgery. To date, there are no randomized, prospective studies available evaluating eradication rates and functional outcomes between the 2 techniques. In this review, both treatment options are described with the most current literature to guide effective surgical decision-making that is cost-effective while decreasing patient morbidity.

Original language	English (US)
Pages (from-to)	S24-S30
Journal	Journal of Arthroplasty
Volume	35
Issue number	3
DOIs	https://doi.org/10.1016/j.arth.2019.10.051
State	Published - Mar 2020
Externally published	Yes

Keywords

infection
periprosthetic joint infection
single-stage revision
treatment
two-stage revision

ASJC Scopus subject areas

Orthopedics and Sports Medicine

Access to Document

10.1016/j.arth.2019.10.051

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Cite this

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abstract = "Periprosthetic joint infection (PJI) is one of the most devastating complications following total joint arthroplasty, accounting for a projected 10,000 revision surgeries per year by 2030. Chronic PJI is complicated by the presence of bacterial biofilm, requiring removal of components, thorough debridement, and administration of antibiotics for effective eradication. Chronic PJI is currently managed with single-stage or 2-stage revision surgery. To date, there are no randomized, prospective studies available evaluating eradication rates and functional outcomes between the 2 techniques. In this review, both treatment options are described with the most current literature to guide effective surgical decision-making that is cost-effective while decreasing patient morbidity.",

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