TY - JOUR
T1 - Single-Walled Carbon Nanotube Sensor Platform for the Study of Extracellular Analytes
AU - Stapleton, Joseph A.
AU - Hofferber, Eric M.
AU - Meier, Jakob
AU - Ramirez, Ivon Acosta
AU - Iverson, Nicole M.
N1 - Funding Information:
The research was supported by a NIH COBRE grant (P30 GM127200) and the National Science Foundation EPSCoR Cooperative Agreement OIA-1557417.
Publisher Copyright:
© 2021 ACS. All rights reserved.
PY - 2021/1/22
Y1 - 2021/1/22
N2 - Single-walled carbon nanotubes (SWNT) are attractive targets for the formation of high-density sensor arrays. Their small size and high reactivity could allow for the spatial and temporal study of extracellular products to a degree which greatly surpasses contemporary sensors. However, current methods of SWNT immobilization produce a low fluorescence yield that requires a combination of high magnification, exposure time, and laser intensity to combat, thus limiting the sensor's applications. In this work, a platform for the immobilization of SWNT sensors with increased fluorescence yield, longevity, fluorescence distribution, and fast reaction times is developed.
AB - Single-walled carbon nanotubes (SWNT) are attractive targets for the formation of high-density sensor arrays. Their small size and high reactivity could allow for the spatial and temporal study of extracellular products to a degree which greatly surpasses contemporary sensors. However, current methods of SWNT immobilization produce a low fluorescence yield that requires a combination of high magnification, exposure time, and laser intensity to combat, thus limiting the sensor's applications. In this work, a platform for the immobilization of SWNT sensors with increased fluorescence yield, longevity, fluorescence distribution, and fast reaction times is developed.
KW - carbon nanotubes
KW - extracellular signaling factor detection
KW - nanotechnology
KW - nitric oxide
KW - platform design
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U2 - 10.1021/acsanm.0c01998
DO - 10.1021/acsanm.0c01998
M3 - Article
C2 - 34355133
AN - SCOPUS:85099035155
SN - 2574-0970
VL - 4
SP - 33
EP - 42
JO - ACS Applied Nano Materials
JF - ACS Applied Nano Materials
IS - 1
ER -