Abstract
A study of the sister chromatid exchange (SCE) frequency in peripheral lymphocytes from 26 human subjects, with in vivo age of the cels as the variable, demonstrated a significant increase in SCE frequency with increasing age of the subject (analysis of variance: p < 0.01). The cells were cultured in Eagle's basal medium with 5-bromodeoxyuridine added to a final concentration of 10 μM. These results are contradictive to the brunt of the literature which indicates that background SCE frequency does not change with age.
Original language | English (US) |
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Pages (from-to) | 67-70 |
Number of pages | 4 |
Journal | Mechanisms of Ageing and Development |
Volume | 16 |
Issue number | 1 |
DOIs | |
State | Published - May 1981 |
ASJC Scopus subject areas
- Aging
- Developmental Biology