Smart flexible wound dressing with wireless drug delivery

Pooria Mostafalu; Suman Amugothu; Ali Tamayol; Sara Bagherifard; Mohsen Akbari; Mehmet R. Dokmeci; Ali Khademhosseini; Sameer Sonkusale

doi:10.1109/BioCAS.2015.7348391

Smart flexible wound dressing with wireless drug delivery

Pooria Mostafalu, Suman Amugothu, Ali Tamayol, Sara Bagherifard, Mohsen Akbari, Mehmet R. Dokmeci, Ali Khademhosseini, Sameer Sonkusale

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

7 Scopus citations

Abstract

Topical drug delivery is a preferred choice to improve the healing process of the chronic wound. However, one of the challenge in topical drug delivery is to find a feasible method to control the drug release in real-Time. To achieve this goal, we created a localized smart flexible bandage containing thermo-responsive drug loaded microparticles encapsulated inside a hydrogel. A flexible heater is in contact with the hydrogel patch. A series of off-The-shelf electronics components including driver of the heater, microcontroller, a wireless radios are assembled in a compact package, and used to control the heater and drug release wirelessly. Paper presents the design and experimental results.

Original language	English (US)
Title of host publication	IEEE Biomedical Circuits and Systems Conference
Subtitle of host publication	Engineering for Healthy Minds and Able Bodies, BioCAS 2015 - Proceedings
Publisher	Institute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)	9781479972333
DOIs	https://doi.org/10.1109/BioCAS.2015.7348391
State	Published - Dec 4 2015
Externally published	Yes
Event	11th IEEE Biomedical Circuits and Systems Conference, BioCAS 2015 - Atlanta, United States Duration: Oct 22 2015 → Oct 24 2015

Publication series

Name	IEEE Biomedical Circuits and Systems Conference: Engineering for Healthy Minds and Able Bodies, BioCAS 2015 - Proceedings

Other

Other	11th IEEE Biomedical Circuits and Systems Conference, BioCAS 2015
Country/Territory	United States
City	Atlanta
Period	10/22/15 → 10/24/15

ASJC Scopus subject areas

Biotechnology
Instrumentation
Biomedical Engineering
Electrical and Electronic Engineering

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10.1109/BioCAS.2015.7348391

Cite this

Mostafalu, P., Amugothu, S., Tamayol, A., Bagherifard, S., Akbari, M., Dokmeci, M. R., Khademhosseini, A., & Sonkusale, S. (2015). Smart flexible wound dressing with wireless drug delivery. In IEEE Biomedical Circuits and Systems Conference: Engineering for Healthy Minds and Able Bodies, BioCAS 2015 - Proceedings [7348391] (IEEE Biomedical Circuits and Systems Conference: Engineering for Healthy Minds and Able Bodies, BioCAS 2015 - Proceedings). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/BioCAS.2015.7348391

Smart flexible wound dressing with wireless drug delivery. / Mostafalu, Pooria; Amugothu, Suman; Tamayol, Ali; Bagherifard, Sara; Akbari, Mohsen; Dokmeci, Mehmet R.; Khademhosseini, Ali; Sonkusale, Sameer.

IEEE Biomedical Circuits and Systems Conference: Engineering for Healthy Minds and Able Bodies, BioCAS 2015 - Proceedings. Institute of Electrical and Electronics Engineers Inc., 2015. 7348391 (IEEE Biomedical Circuits and Systems Conference: Engineering for Healthy Minds and Able Bodies, BioCAS 2015 - Proceedings).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Mostafalu, P, Amugothu, S, Tamayol, A, Bagherifard, S, Akbari, M, Dokmeci, MR, Khademhosseini, A & Sonkusale, S 2015, Smart flexible wound dressing with wireless drug delivery. in IEEE Biomedical Circuits and Systems Conference: Engineering for Healthy Minds and Able Bodies, BioCAS 2015 - Proceedings., 7348391, IEEE Biomedical Circuits and Systems Conference: Engineering for Healthy Minds and Able Bodies, BioCAS 2015 - Proceedings, Institute of Electrical and Electronics Engineers Inc., 11th IEEE Biomedical Circuits and Systems Conference, BioCAS 2015, Atlanta, United States, 10/22/15. https://doi.org/10.1109/BioCAS.2015.7348391

Mostafalu P, Amugothu S, Tamayol A, Bagherifard S, Akbari M, Dokmeci MR et al. Smart flexible wound dressing with wireless drug delivery. In IEEE Biomedical Circuits and Systems Conference: Engineering for Healthy Minds and Able Bodies, BioCAS 2015 - Proceedings. Institute of Electrical and Electronics Engineers Inc. 2015. 7348391. (IEEE Biomedical Circuits and Systems Conference: Engineering for Healthy Minds and Able Bodies, BioCAS 2015 - Proceedings). https://doi.org/10.1109/BioCAS.2015.7348391

Mostafalu, Pooria ; Amugothu, Suman ; Tamayol, Ali ; Bagherifard, Sara ; Akbari, Mohsen ; Dokmeci, Mehmet R. ; Khademhosseini, Ali ; Sonkusale, Sameer. / Smart flexible wound dressing with wireless drug delivery. IEEE Biomedical Circuits and Systems Conference: Engineering for Healthy Minds and Able Bodies, BioCAS 2015 - Proceedings. Institute of Electrical and Electronics Engineers Inc., 2015. (IEEE Biomedical Circuits and Systems Conference: Engineering for Healthy Minds and Able Bodies, BioCAS 2015 - Proceedings).

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abstract = "Topical drug delivery is a preferred choice to improve the healing process of the chronic wound. However, one of the challenge in topical drug delivery is to find a feasible method to control the drug release in real-Time. To achieve this goal, we created a localized smart flexible bandage containing thermo-responsive drug loaded microparticles encapsulated inside a hydrogel. A flexible heater is in contact with the hydrogel patch. A series of off-The-shelf electronics components including driver of the heater, microcontroller, a wireless radios are assembled in a compact package, and used to control the heater and drug release wirelessly. Paper presents the design and experimental results.",

author = "Pooria Mostafalu and Suman Amugothu and Ali Tamayol and Sara Bagherifard and Mohsen Akbari and Dokmeci, {Mehmet R.} and Ali Khademhosseini and Sameer Sonkusale",

note = "Funding Information: National Science Foundation EFRI-1240443 Publisher Copyright: {\textcopyright} 2015 IEEE.; 11th IEEE Biomedical Circuits and Systems Conference, BioCAS 2015 ; Conference date: 22-10-2015 Through 24-10-2015",

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AB - Topical drug delivery is a preferred choice to improve the healing process of the chronic wound. However, one of the challenge in topical drug delivery is to find a feasible method to control the drug release in real-Time. To achieve this goal, we created a localized smart flexible bandage containing thermo-responsive drug loaded microparticles encapsulated inside a hydrogel. A flexible heater is in contact with the hydrogel patch. A series of off-The-shelf electronics components including driver of the heater, microcontroller, a wireless radios are assembled in a compact package, and used to control the heater and drug release wirelessly. Paper presents the design and experimental results.

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Smart flexible wound dressing with wireless drug delivery

Abstract

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