Snapshot: Trial Types in Precision Medicine

Dane Dickson; Jennifer Johnson; Raymond Bergan; Rebecca Owens; Vivek Subbiah; Razelle Kurzrock

doi:10.1016/j.cell.2020.02.032

Snapshot: Trial Types in Precision Medicine

Dane Dickson, Jennifer Johnson, Raymond Bergan, Rebecca Owens, Vivek Subbiah, Razelle Kurzrock

Research output: Contribution to journal › Comment/debate › peer-review

12 Scopus citations

Abstract

Integrating precision diagnostics into personalized treatments requires understanding how biomarkers relate to clinical outcomes. Various clinical data collection methods exist, each with strengths and weaknesses. Interventional data are high quality but narrowly focused. Real-world data (RWD) provide broader information but with variable quality. Master protocols allow better efficiency in data collection. The master observational trial bridges the gap between interventional and retrospective RWD collection methods. To view this SnapShot, open or download the PDF.

Original language	English (US)
Pages (from-to)	208-208.e1
Journal	Cell
Volume	181
Issue number	1
DOIs	https://doi.org/10.1016/j.cell.2020.02.032
State	Published - Apr 2 2020
Externally published	Yes

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology

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10.1016/j.cell.2020.02.032

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abstract = "Integrating precision diagnostics into personalized treatments requires understanding how biomarkers relate to clinical outcomes. Various clinical data collection methods exist, each with strengths and weaknesses. Interventional data are high quality but narrowly focused. Real-world data (RWD) provide broader information but with variable quality. Master protocols allow better efficiency in data collection. The master observational trial bridges the gap between interventional and retrospective RWD collection methods. To view this SnapShot, open or download the PDF.",

author = "Dane Dickson and Jennifer Johnson and Raymond Bergan and Rebecca Owens and Vivek Subbiah and Razelle Kurzrock",

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AU - Johnson, Jennifer

AU - Bergan, Raymond

AU - Owens, Rebecca

AU - Subbiah, Vivek

AU - Kurzrock, Razelle

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AB - Integrating precision diagnostics into personalized treatments requires understanding how biomarkers relate to clinical outcomes. Various clinical data collection methods exist, each with strengths and weaknesses. Interventional data are high quality but narrowly focused. Real-world data (RWD) provide broader information but with variable quality. Master protocols allow better efficiency in data collection. The master observational trial bridges the gap between interventional and retrospective RWD collection methods. To view this SnapShot, open or download the PDF.

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Snapshot: Trial Types in Precision Medicine

Abstract

ASJC Scopus subject areas

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