Abstract
Alkyl aryl ether formation is a frequently employed reaction in organic synthesis. Ullmann condensation is an alternative method to the widely used Mitsunobu reaction and is very useful in situations where application of the Mitsunobu reaction is limited. By application of this reaction to solid-phase synthesis of a series of alkyl aryl ethers, reaction conditions (catalyst, solvent, temperature, time, etc.) for a sterically hindered class of alcohols were investigated and optimized. A range of aryl halides was used to explore the scope of the reaction in solid phase.
Original language | English (US) |
---|---|
Pages (from-to) | 536-539 |
Number of pages | 4 |
Journal | Journal of Combinatorial Chemistry |
Volume | 4 |
Issue number | 5 |
DOIs | |
State | Published - Sep 2002 |
Externally published | Yes |
ASJC Scopus subject areas
- Chemistry(all)