Solitary esophageal leiomyoma with eosinophilic infiltrate: Case report and review of the literature

SUMMARY: Leiomyomas are common benign tumors of the esophagus representing 10% of all mesenchymal tumors of the gastrointestinal tract. Prominent numbers of eosinophils involving a leiomyoma have only rarely been described. They have never been described involving a solitary leiomyoma of the esophagus. We present an unusual case of a solitary esophageal leiomyoma with a prominent number of eosinophils and mast cells, review the previous literature regarding this topic and discuss possible causes of the eosinophil infiltrate.