Specific reading disability: Identification of an inherited form through linkage analysis

Shelley D. Smith; W. J. Kimberling; Bruce F. Pennington; Herbert A. Lubs

doi:10.1126/science.6828864

Specific reading disability: Identification of an inherited form through linkage analysis

Shelley D. Smith, W. J. Kimberling, Bruce F. Pennington, Herbert A. Lubs

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Abstract

Linkage analysis in families with apparent autosomal dominant reading disability produced a lod score of 3.241. Since the traditionally accepted significance level for linkage is a lod score of 3.0, these results strongly suggest that a gene playing a major etiologic role in one form of reading disability is on chromosome 15.

Original language	English (US)
Pages (from-to)	1341-1343
Number of pages	3
Journal	Science
Volume	219
Issue number	4590
DOIs	https://doi.org/10.1126/science.6828864
State	Published - 1983

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@article{978a64dde47c4b59a814bca7d8a1d419,

title = "Specific reading disability: Identification of an inherited form through linkage analysis",

abstract = "Linkage analysis in families with apparent autosomal dominant reading disability produced a lod score of 3.241. Since the traditionally accepted significance level for linkage is a lod score of 3.0, these results strongly suggest that a gene playing a major etiologic role in one form of reading disability is on chromosome 15.",

author = "Smith, {Shelley D.} and Kimberling, {W. J.} and Pennington, {Bruce F.} and Lubs, {Herbert A.}",

year = "1983",

doi = "10.1126/science.6828864",

language = "English (US)",

volume = "219",

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AU - Smith, Shelley D.

AU - Kimberling, W. J.

AU - Pennington, Bruce F.

AU - Lubs, Herbert A.

PY - 1983

Y1 - 1983

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AB - Linkage analysis in families with apparent autosomal dominant reading disability produced a lod score of 3.241. Since the traditionally accepted significance level for linkage is a lod score of 3.0, these results strongly suggest that a gene playing a major etiologic role in one form of reading disability is on chromosome 15.

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JO - Science

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Specific reading disability: Identification of an inherited form through linkage analysis

Abstract

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