Statistical Methods for the Quantitative Genetic Analysis of High-Throughput Phenotyping Data

Gota Morota, Diego Jarquin, Malachy T. Campbell, Hiroyoshi Iwata

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The advent of plant phenomics, coupled with the wealth of genotypic data generated by next-generation sequencing technologies, provides exciting new resources for investigations into and improvement of complex traits. However, these new technologies also bring new challenges in quantitative genetics, namely, a need for the development of robust frameworks that can accommodate these high-dimensional data. In this chapter, we describe methods for the statistical analysis of high-throughput phenotyping (HTP) data with the goal of enhancing the prediction accuracy of genomic selection (GS). Following the Introduction in Sec. 1, Sec. 2 discusses field-based HTP, including the use of unoccupied aerial vehicles and light detection and ranging, as well as how we can achieve increased genetic gain by utilizing image data derived from HTP. Section 3 considers extending commonly used GS models to integrate HTP data as covariates associated with the principal trait response, such as yield. Particular focus is placed on single-trait, multi-trait, and genotype by environment interaction models. One unique aspect of HTP data is that phenomics platforms often produce large-scale data with high spatial and temporal resolution for capturing dynamic growth, development, and stress responses. Section 4 discusses the utility of a random regression model for performing longitudinal modeling. The chapter concludes with a discussion of some standing issues.

Original languageEnglish (US)
Title of host publicationMethods in Molecular Biology
PublisherHumana Press Inc.
Pages269-296
Number of pages28
DOIs
StatePublished - 2022
Externally publishedYes

Publication series

NameMethods in Molecular Biology
Volume2539
ISSN (Print)1064-3745
ISSN (Electronic)1940-6029

Keywords

  • Genetic gain
  • High-throughput phenotyping
  • Image data
  • Longitudinal trait
  • Quantitative genetics

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics

Fingerprint

Dive into the research topics of 'Statistical Methods for the Quantitative Genetic Analysis of High-Throughput Phenotyping Data'. Together they form a unique fingerprint.

Cite this