Abstract

It is now accepted that neurogenesis continues throughout life, contrary to the previously held dogma that no new neurons are produced in the adult human brain. Neurogenesis during development and throughout adult life is a result of the proliferation, migration, and differentiation of neural stem cells (NSC). NSC are cells that can differentiate into all the cells of the central nervous system (CNS) and self-renew while retaining their multipotential capabilities. Numerous factors contribute to the survival, proliferation, migration, and differentiation of NSC. These factors include, but are not limited to, chemokines, growth factors, and neurotransmitters.

Original languageEnglish (US)
Title of host publicationNeuroimmune Pharmacology
PublisherSpringer US
Pages151-170
Number of pages20
ISBN (Print)9780387725727
DOIs
StatePublished - 2008

Keywords

  • Chemokines
  • Differentiation
  • Growth factors
  • Microglia
  • Neurogenesis
  • Neurotransmitters
  • Proliferation
  • Self-renewal
  • Stem cell

ASJC Scopus subject areas

  • Neuroscience(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)

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  • Cite this

    Peng, H., Whitney, N., Tang, K., Toews, M., & Zheng, J. (2008). Stem cells. In Neuroimmune Pharmacology (pp. 151-170). Springer US. https://doi.org/10.1007/978-0-387-72573-4_13