Steric and electrostatic complementarity in the assembly of two-dimensional virus arrays

Chin Li Cheung; Alexander I. Rubinstein; Erik J. Peterson; Anju Chatterji; Renat F. Sabirianov; Wai Ning Mei; Tianwei Lin; John E. Johnson; James J. Deyoreo

doi:10.1021/la903114s

Steric and electrostatic complementarity in the assembly of two-dimensional virus arrays

Chin Li Cheung, Alexander I. Rubinstein, Erik J. Peterson, Anju Chatterji, Renat F. Sabirianov, Wai Ning Mei, Tianwei Lin, John E. Johnson, James J. Deyoreo

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

A highly ordered assembly of biological molecules provides a powerful means to study the organizational principles of objects at the nanoscale. Two-dimensional cowpea mosaic virus arrays were assembled in an ordered manner on mica using osmotic depletion effects and a drop-and-dry method. The packing of the virus array was controlled systematically from rhombic packing to hexagonal packing by modulating the concentrations of polyethylene glycol) surfactant in the virus solutions. The orientation and packing symmetry of the virus arrays were found to be tuned by the concentrations of surfactants in the sample solutions. A phenomenological model for the present system is proposed to explain the assembly array morphology under the influence of the surfactant. Steric and electrostatic complementarity of neighboring virus capsids is found to be the key factors in controlling the symmetry of packing.

Original language	English (US)
Pages (from-to)	3498-3505
Number of pages	8
Journal	Langmuir
Volume	26
Issue number	5
DOIs	https://doi.org/10.1021/la903114s
State	Published - Mar 2 2010

ASJC Scopus subject areas

Materials Science(all)
Condensed Matter Physics
Surfaces and Interfaces
Spectroscopy
Electrochemistry

Access to Document

10.1021/la903114s

Cite this

@article{1e641c743d0b442783639398afd1c087,

title = "Steric and electrostatic complementarity in the assembly of two-dimensional virus arrays",

abstract = "A highly ordered assembly of biological molecules provides a powerful means to study the organizational principles of objects at the nanoscale. Two-dimensional cowpea mosaic virus arrays were assembled in an ordered manner on mica using osmotic depletion effects and a drop-and-dry method. The packing of the virus array was controlled systematically from rhombic packing to hexagonal packing by modulating the concentrations of polyethylene glycol) surfactant in the virus solutions. The orientation and packing symmetry of the virus arrays were found to be tuned by the concentrations of surfactants in the sample solutions. A phenomenological model for the present system is proposed to explain the assembly array morphology under the influence of the surfactant. Steric and electrostatic complementarity of neighboring virus capsids is found to be the key factors in controlling the symmetry of packing.",

author = "Cheung, {Chin Li} and Rubinstein, {Alexander I.} and Peterson, {Erik J.} and Anju Chatterji and Sabirianov, {Renat F.} and Mei, {Wai Ning} and Tianwei Lin and Johnson, {John E.} and Deyoreo, {James J.}",

year = "2010",

month = mar,

day = "2",

doi = "10.1021/la903114s",

language = "English (US)",

volume = "26",

pages = "3498--3505",

journal = "Langmuir",

issn = "0743-7463",

publisher = "American Chemical Society",

number = "5",

}

TY - JOUR

T1 - Steric and electrostatic complementarity in the assembly of two-dimensional virus arrays

AU - Cheung, Chin Li

AU - Rubinstein, Alexander I.

AU - Peterson, Erik J.

AU - Chatterji, Anju

AU - Sabirianov, Renat F.

AU - Mei, Wai Ning

AU - Lin, Tianwei

AU - Johnson, John E.

AU - Deyoreo, James J.

PY - 2010/3/2

Y1 - 2010/3/2

N2 - A highly ordered assembly of biological molecules provides a powerful means to study the organizational principles of objects at the nanoscale. Two-dimensional cowpea mosaic virus arrays were assembled in an ordered manner on mica using osmotic depletion effects and a drop-and-dry method. The packing of the virus array was controlled systematically from rhombic packing to hexagonal packing by modulating the concentrations of polyethylene glycol) surfactant in the virus solutions. The orientation and packing symmetry of the virus arrays were found to be tuned by the concentrations of surfactants in the sample solutions. A phenomenological model for the present system is proposed to explain the assembly array morphology under the influence of the surfactant. Steric and electrostatic complementarity of neighboring virus capsids is found to be the key factors in controlling the symmetry of packing.

AB - A highly ordered assembly of biological molecules provides a powerful means to study the organizational principles of objects at the nanoscale. Two-dimensional cowpea mosaic virus arrays were assembled in an ordered manner on mica using osmotic depletion effects and a drop-and-dry method. The packing of the virus array was controlled systematically from rhombic packing to hexagonal packing by modulating the concentrations of polyethylene glycol) surfactant in the virus solutions. The orientation and packing symmetry of the virus arrays were found to be tuned by the concentrations of surfactants in the sample solutions. A phenomenological model for the present system is proposed to explain the assembly array morphology under the influence of the surfactant. Steric and electrostatic complementarity of neighboring virus capsids is found to be the key factors in controlling the symmetry of packing.

UR - http://www.scopus.com/inward/record.url?scp=77749298762&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77749298762&partnerID=8YFLogxK

U2 - 10.1021/la903114s

DO - 10.1021/la903114s

M3 - Article

C2 - 19754157

AN - SCOPUS:77749298762

SN - 0743-7463

VL - 26

SP - 3498

EP - 3505

JO - Langmuir

JF - Langmuir

IS - 5

ER -

Steric and electrostatic complementarity in the assembly of two-dimensional virus arrays

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this