Strategies for prevention of health care-associated infections in the NICU

Richard A. Polin, Susan Denson, Michael T. Brady, Lu Ann Papile, Jill E. Baley, Waldemar A. Carlo, James J. Cummings, Praveen Kumar, Rosemarie C. Tan, Kristi L. Watterberg, Carrie L. Byington, H. Dele Davies, Kathryn M. Edwards, Mary P. Glode, Mary Anne Jackson, Harry L. Keyserling, Yvonne A. Maldonado, Dennis L. Murray, Walter A. Orenstein, Gordon E. SchutzeRodney E. Willoughby, Theoklis E. Zaoutis

Research output: Contribution to journalArticlepeer-review

89 Scopus citations


Health care-associated infections in the NICU result in increased morbidity and mortality, prolonged lengths of stay, and increased medical costs. Neonates are at high risk of acquiring health care- associated infections because of impaired host-defense mechanisms, limited amounts of protective endogenous flora on skin and mucosal surfaces at time of birth, reduced barrier function of their skin, use of invasive procedures and devices, and frequent exposure to broadspectrum antibiotic agents. This clinical report reviews management and prevention of health care-associated infections in newborn infants.

Original languageEnglish (US)
Pages (from-to)e1085-e1093
Issue number4
StatePublished - Apr 2012
Externally publishedYes


  • Antibiotics
  • Health care-associated infection
  • NICU
  • Neonatal icu
  • Neonate
  • Newborn
  • Nosocomial infection

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


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