Structural insight into geranylgeranyl diphosphate synthase (GGDPS) for cancer therapy

Keyphrases

• Cancer Therapy 100%
• Geranylgeranyl Diphosphate Synthase 100%
• Structural Insights 100%
• Inhibitor Development 33%
• Anticancer Therapy 16%
• Drug Target 16%
• Surface Molecules 16%
• Higher-order Structure 16%
• Small Molecule Inhibitors 16%
• Active Sites 16%
• Enzyme Binding 16%
• Structure Formation 16%
• Target Enzyme 16%
• Substrate Binding 16%
• Inhibitor Binding 16%
• Isoprenoids 16%
• Structure-based Drug Design 16%
• Product Interaction 16%
• Enzyme Structure 16%
• Electrostatic Surface 16%
• Inhibitor Selectivity 16%
• Protein Geranylgeranylation 16%
• Nitrogen-containing Bisphosphonates 16%
• AlphaFold 16%

Biochemistry, Genetics and Molecular Biology

• Synthase 100%
• Geranylgeranyl Pyrophosphate 100%
• Enzyme 16%
• Surface Property 16%
• Small Molecule 16%
• Static Electricity 16%
• Active Site 16%
• Enzyme Structure 16%
• Geranylgeranylation 16%

Pharmacology, Toxicology and Pharmaceutical Science

• Malignant Neoplasm 100%
• Farnesyl Trans Transferase 100%
• Bisphosphonic Acid Derivative 16%
• Drug Development 16%
• Isoprenoid 16%
• Enzyme Interaction 16%