TY - JOUR
T1 - Structure-activity studies of aldose reductase inhibitors containing the 4-oxo-4H-chromen ring system
AU - Kador, Peter F.
AU - Sharpless, Norman E.
PY - 1978/3
Y1 - 1978/3
N2 - Various 4-oxo-4H-chromen-2-carboxylic acids and their derivatives were screened for aldose reductase inhibitory activity. Their inhibitory response along with that of several flavonoids has been correlated with simple Hückel molecular orbital calculations. From these results a possible mode of action is postulated.
AB - Various 4-oxo-4H-chromen-2-carboxylic acids and their derivatives were screened for aldose reductase inhibitory activity. Their inhibitory response along with that of several flavonoids has been correlated with simple Hückel molecular orbital calculations. From these results a possible mode of action is postulated.
UR - http://www.scopus.com/inward/record.url?scp=0017894486&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0017894486&partnerID=8YFLogxK
U2 - 10.1016/0301-4622(78)85025-X
DO - 10.1016/0301-4622(78)85025-X
M3 - Article
C2 - 417745
AN - SCOPUS:0017894486
VL - 8
SP - 81
EP - 85
JO - Biophysical Chemistry
JF - Biophysical Chemistry
SN - 0301-4622
IS - 1
ER -