Structure-Related Thrombosis Involving a Porcine Xenograft Valve

Rodney D. McComb, Fred D. Stahmann, William N. O'Connor, Edward P. Todd

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


A patient developed acute congestive heart failure following chordal rupture and underwent mitral valve replacement with a porcine xenograft. He recovered adequate hemodynamic function but died one month later with widespread bronchopneumonia. Postmortem examination revealed a prominent muscular shelf in the right coronary leaflet of the xenograft, and focal thrombosis involving the adjacent sewing ring and left atrial wall. The location of the thrombus suggests that it formed as a result of local stasis behind the large muscular shelf. Limiting the size of this muscular shelf by valve selection and construction may reduce the thrombogenicity of this prosthesis.

Original languageEnglish (US)
Pages (from-to)191-193
Number of pages3
JournalAnnals of Thoracic Surgery
Issue number2
StatePublished - 1979
Externally publishedYes

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine


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