Studies on production of L-3,4-dihydroxyphenylalanine by clay adsorbed tyrosinase

Neeru Munjal Sharma; Sushil Kumar; Surender K. Sawhney

Studies on production of L-3,4-dihydroxyphenylalanine by clay adsorbed tyrosinase

Neeru Munjal Sharma, Sushil Kumar, Surender K. Sawhney

Research output: Contribution to journal › Article › peer-review

Abstract

An enzyme reactor for production of L-3,4-dihydroxy phenylalanine (L-DOPA), an antiparkinsonian agent is constructed by using Fuller's earth adsorbed tyrosinase engulfed in dialysis sac. This permits easy retrieval of the adsorbed enzyme from reaction mixture for processing of fresh batch, thereby preventing the phenomenon of product inhibition to some extent. In this modified batch reactor, 123 mg L-DOPA/L/h is produced.

Original language	English (US)
Pages (from-to)	921-925
Number of pages	5
Journal	Journal of Scientific and Industrial Research
Volume	62
Issue number	9
State	Published - Sep 2003
Externally published	Yes

Keywords

Clay adsorbed tyrosinase
Fuller's earth
L-DOPA
Parkinson's disease
Tyrosinase

ASJC Scopus subject areas

General

Cite this

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abstract = "An enzyme reactor for production of L-3,4-dihydroxy phenylalanine (L-DOPA), an antiparkinsonian agent is constructed by using Fuller's earth adsorbed tyrosinase engulfed in dialysis sac. This permits easy retrieval of the adsorbed enzyme from reaction mixture for processing of fresh batch, thereby preventing the phenomenon of product inhibition to some extent. In this modified batch reactor, 123 mg L-DOPA/L/h is produced.",

keywords = "Clay adsorbed tyrosinase, Fuller's earth, L-DOPA, Parkinson's disease, Tyrosinase",

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AU - Sharma, Neeru Munjal

AU - Kumar, Sushil

AU - Sawhney, Surender K.

PY - 2003/9

Y1 - 2003/9

N2 - An enzyme reactor for production of L-3,4-dihydroxy phenylalanine (L-DOPA), an antiparkinsonian agent is constructed by using Fuller's earth adsorbed tyrosinase engulfed in dialysis sac. This permits easy retrieval of the adsorbed enzyme from reaction mixture for processing of fresh batch, thereby preventing the phenomenon of product inhibition to some extent. In this modified batch reactor, 123 mg L-DOPA/L/h is produced.

AB - An enzyme reactor for production of L-3,4-dihydroxy phenylalanine (L-DOPA), an antiparkinsonian agent is constructed by using Fuller's earth adsorbed tyrosinase engulfed in dialysis sac. This permits easy retrieval of the adsorbed enzyme from reaction mixture for processing of fresh batch, thereby preventing the phenomenon of product inhibition to some extent. In this modified batch reactor, 123 mg L-DOPA/L/h is produced.

KW - Clay adsorbed tyrosinase

KW - Fuller's earth

KW - L-DOPA

KW - Parkinson's disease

KW - Tyrosinase

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JF - Journal of Scientific and Industrial Research

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ER -

Studies on production of L-3,4-dihydroxyphenylalanine by clay adsorbed tyrosinase

Abstract

Keywords

ASJC Scopus subject areas

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