Studies on production of L-3,4-dihydroxyphenylalanine by clay adsorbed tyrosinase

Neeru Munjal Sharma, Sushil Kumar, Surender K. Sawhney

Research output: Contribution to journalArticlepeer-review

Abstract

An enzyme reactor for production of L-3,4-dihydroxy phenylalanine (L-DOPA), an antiparkinsonian agent is constructed by using Fuller's earth adsorbed tyrosinase engulfed in dialysis sac. This permits easy retrieval of the adsorbed enzyme from reaction mixture for processing of fresh batch, thereby preventing the phenomenon of product inhibition to some extent. In this modified batch reactor, 123 mg L-DOPA/L/h is produced.

Original languageEnglish (US)
Pages (from-to)921-925
Number of pages5
JournalJournal of Scientific and Industrial Research
Volume62
Issue number9
StatePublished - Sep 2003
Externally publishedYes

Keywords

  • Clay adsorbed tyrosinase
  • Fuller's earth
  • L-DOPA
  • Parkinson's disease
  • Tyrosinase

ASJC Scopus subject areas

  • General

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