Subantimicrobial-Dose Doxycycline Effects on Alveolar Bone Loss in Postmenopausal Women: Example of a Randomized Controlled Clinical Trial

Julie A. Stoner, Jeffrey B. Payne

Research output: Chapter in Book/Report/Conference proceedingChapter

Original languageEnglish (US)
Title of host publicationStatistical and Methodological Aspects of Oral Health Research
Number of pages18
ISBN (Electronic)9780470744116
ISBN (Print)9780470517925
StatePublished - Mar 6 2009


  • Clinical outcome measures and relative clinical attachment level (RCAL) measurement
  • Computer-assisted densitometric image analysis (CADIA) method
  • Estrogen deficiency in postmenopausal women and associated systemic bone mineral density loss
  • Hormone replacement therapy (HRT)
  • Sample size justification and CADIA measure of alveolar bone density
  • Statistical analysis methods and baseline RCAL measures by treatment group
  • Subantimicrobial dose doxycycline (SDD)
  • Subantimicrobial-dose doxycycline effects on alveolar bone loss in postmenopausal women
  • Subject recruitment and follow-up
  • University of Nebraska Medical Center College of Dentistry, Lincoln, NE (UNMC)

ASJC Scopus subject areas

  • General Mathematics

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