1. Histamine-N-methyltransferase (HMT) from jejunal mucosa of rats, guinea pigs and rhesus monkeys was localized in the soluble fraction. 2. Diamine oxidase (DAO) from jejunal mucosa of rats and rhesus monkeys was localized in the soluble fraction. 3. Guinea pig jejunal mucosa had no observable DAO activity. 4. The Km's observed for jejunal mucosa HMT were 33.2 μM for rat, 114 μM for rhesus monkey and 7.1 μM for guinea pig. 5. The Km's observed for jejunal mucosa DAO were 0.21 mM for rat and 0.26 mM for rhesus monkey. 6. Substrate inhibition was encountered at high substrate concentrations with rat HMT and rat and monkey DAO.
|Original language||English (US)|
|Number of pages||6|
|Journal||Comparative Biochemistry and Physiology. Part C, Comparative|
|State||Published - 1979|
ASJC Scopus subject areas