Successful small bowel allotransplantation in dogs with cyclosporine and prednisone

Hector S. Diliz-Perez, John McClure, Carlos Bedetti, He Qun Hong, Eduardo De Santibanes, Byers W. Shaw, David Van Thiel, Shunzaburo Iwatsuki, Thomas E. Starzl

Research output: Contribution to journalArticle

61 Scopus citations

Abstract

Twelve dogs had transplantation of almost the entire small intestine in the orthotopic location; immunosuppression was with cyclosporine and prednisone. Half the dogs had survival of at least one month, and a third lived for at least four months. Two of the animals are still living after 550 and 555 days. Maintenance of nutrition, and absorption of D-xylose and fat were better than in control animals with an iatrogenic short gut syndrome, but distinctly worse than that of normal dogs.

Original languageEnglish (US)
Pages (from-to)126-129
Number of pages4
JournalTransplantation
Volume37
Issue number2
DOIs
StatePublished - Feb 1984

ASJC Scopus subject areas

  • Transplantation

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    Diliz-Perez, H. S., McClure, J., Bedetti, C., Hong, H. Q., De Santibanes, E., Shaw, B. W., Van Thiel, D., Iwatsuki, S., & Starzl, T. E. (1984). Successful small bowel allotransplantation in dogs with cyclosporine and prednisone. Transplantation, 37(2), 126-129. https://doi.org/10.1097/00007890-198402000-00002