Successful small bowel allotransplantation in dogs with cyclosporine and prednisone

Hector S. Diliz-Perez; John McClure; Carlos Bedetti; He Qun Hong; Eduardo De Santibanes; Byers W. Shaw; David Van Thiel; Shunzaburo Iwatsuki; Thomas E. Starzl

doi:10.1097/00007890-198402000-00002

Successful small bowel allotransplantation in dogs with cyclosporine and prednisone

Hector S. Diliz-Perez, John McClure, Carlos Bedetti, He Qun Hong, Eduardo De Santibanes, Byers W. Shaw, David Van Thiel, Shunzaburo Iwatsuki, Thomas E. Starzl

Research output: Contribution to journal › Article › peer-review

66 Scopus citations

Abstract

Twelve dogs had transplantation of almost the entire small intestine in the orthotopic location; immunosuppression was with cyclosporine and prednisone. Half the dogs had survival of at least one month, and a third lived for at least four months. Two of the animals are still living after 550 and 555 days. Maintenance of nutrition, and absorption of D-xylose and fat were better than in control animals with an iatrogenic short gut syndrome, but distinctly worse than that of normal dogs.

Original language	English (US)
Pages (from-to)	126-129
Number of pages	4
Journal	Transplantation
Volume	37
Issue number	2
DOIs	https://doi.org/10.1097/00007890-198402000-00002
State	Published - Feb 1984
Externally published	Yes

ASJC Scopus subject areas

Transplantation

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title = "Successful small bowel allotransplantation in dogs with cyclosporine and prednisone",

abstract = "Twelve dogs had transplantation of almost the entire small intestine in the orthotopic location; immunosuppression was with cyclosporine and prednisone. Half the dogs had survival of at least one month, and a third lived for at least four months. Two of the animals are still living after 550 and 555 days. Maintenance of nutrition, and absorption of D-xylose and fat were better than in control animals with an iatrogenic short gut syndrome, but distinctly worse than that of normal dogs.",

author = "Diliz-Perez, {Hector S.} and John McClure and Carlos Bedetti and Hong, {He Qun} and {De Santibanes}, Eduardo and Shaw, {Byers W.} and {Van Thiel}, David and Shunzaburo Iwatsuki and Starzl, {Thomas E.}",

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AU - Diliz-Perez, Hector S.

AU - McClure, John

AU - Bedetti, Carlos

AU - Hong, He Qun

AU - De Santibanes, Eduardo

AU - Shaw, Byers W.

AU - Van Thiel, David

AU - Iwatsuki, Shunzaburo

AU - Starzl, Thomas E.

PY - 1984/2

Y1 - 1984/2

N2 - Twelve dogs had transplantation of almost the entire small intestine in the orthotopic location; immunosuppression was with cyclosporine and prednisone. Half the dogs had survival of at least one month, and a third lived for at least four months. Two of the animals are still living after 550 and 555 days. Maintenance of nutrition, and absorption of D-xylose and fat were better than in control animals with an iatrogenic short gut syndrome, but distinctly worse than that of normal dogs.

AB - Twelve dogs had transplantation of almost the entire small intestine in the orthotopic location; immunosuppression was with cyclosporine and prednisone. Half the dogs had survival of at least one month, and a third lived for at least four months. Two of the animals are still living after 550 and 555 days. Maintenance of nutrition, and absorption of D-xylose and fat were better than in control animals with an iatrogenic short gut syndrome, but distinctly worse than that of normal dogs.

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ER -

Successful small bowel allotransplantation in dogs with cyclosporine and prednisone

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