Successful small bowel allotransplantation in dogs with cyclosporine and prednisone

Hector S. Diliz-Perez, John McClure, Carlos Bedetti, He Qun Hong, Eduardo De Santibanes, Byers W. Shaw, David Van Thiel, Shunzaburo Iwatsuki, Thomas E. Starzl

Research output: Contribution to journalArticlepeer-review

65 Scopus citations


Twelve dogs had transplantation of almost the entire small intestine in the orthotopic location; immunosuppression was with cyclosporine and prednisone. Half the dogs had survival of at least one month, and a third lived for at least four months. Two of the animals are still living after 550 and 555 days. Maintenance of nutrition, and absorption of D-xylose and fat were better than in control animals with an iatrogenic short gut syndrome, but distinctly worse than that of normal dogs.

Original languageEnglish (US)
Pages (from-to)126-129
Number of pages4
Issue number2
StatePublished - Feb 1984
Externally publishedYes

ASJC Scopus subject areas

  • Transplantation


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