Surgical Approach to Endocrine Hypertension in Patients with Adrenal Disorders

Jessica Shank, Jason D. Prescott, Aarti Mathur

Research output: Contribution to journalReview articlepeer-review

4 Scopus citations


Increased hormonal secretion of aldosterone, cortisol, or catecholamines from an adrenal gland can produce a variety of undesirable symptoms, including hypertension, which may be the initial presenting symptom. Consequences of secondary hypertension can result in potential cardiovascular and cerebrovascular complications at higher rates than in those with essential hypertension. Once a biochemical diagnosis is confirmed, targeted pharmacotherapy can be initiated to improve hypertension and may be corrected with surgical intervention. Adrenalectomy can be curative and can reverse the risk of cardiovascular sequelae once blood pressure control is achieved. This article discusses perioperative and operative considerations of adrenal causes of hypertension.

Original languageEnglish (US)
Pages (from-to)875-885
Number of pages11
JournalEndocrinology and Metabolism Clinics of North America
Issue number4
StatePublished - Dec 2019
Externally publishedYes


  • Adrenalectomy
  • Cushing syndrome
  • Endocrine hypertension
  • Hyperaldosteronism
  • Hypercortisolism
  • Pheochromocytoma
  • Secondary hypertension

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology


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