Abstract
Purpose of Review: To review and update surgeons about the evolving complexities in the surgical management of melanoma including lymph node staging and treatment. Recent Findings: Primary resection with adequate margins continues to be the standard of care for localized cutaneous melanoma. Sentinel lymph node biopsy is confirmed to be a powerful tool due to its prognostic value and informative guidance for adjuvant treatments and surveillance. Due to the lack of benefit in melanoma-specific survival and distant metastasis-free survival, completion lymph node dissection is not performed routinely after a positive sentinel lymph node biopsy. Neoadjuvant systemic treatment approaches for advanced loco-regional disease show promise in phase I and II clinical trial data, and phase III studies. Summary: The surgical management of cutaneous melanoma continues to evolve with further de-escalation of the extent of excision of primary melanomas and the management of lymph node disease.
Original language | English (US) |
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Pages (from-to) | 1425-1432 |
Number of pages | 8 |
Journal | Current Oncology Reports |
Volume | 24 |
Issue number | 11 |
DOIs | |
State | Published - Nov 2022 |
Keywords
- Immunotherapy
- Lymphadenectomy
- Margins
- Melanoma
- Neoadjuvant immunotherapy
- Surgical oncology
ASJC Scopus subject areas
- Oncology