Surgical Management of Melanoma: Advances and Updates

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Abstract

Purpose of Review: To review and update surgeons about the evolving complexities in the surgical management of melanoma including lymph node staging and treatment. Recent Findings: Primary resection with adequate margins continues to be the standard of care for localized cutaneous melanoma. Sentinel lymph node biopsy is confirmed to be a powerful tool due to its prognostic value and informative guidance for adjuvant treatments and surveillance. Due to the lack of benefit in melanoma-specific survival and distant metastasis-free survival, completion lymph node dissection is not performed routinely after a positive sentinel lymph node biopsy. Neoadjuvant systemic treatment approaches for advanced loco-regional disease show promise in phase I and II clinical trial data, and phase III studies. Summary: The surgical management of cutaneous melanoma continues to evolve with further de-escalation of the extent of excision of primary melanomas and the management of lymph node disease.

Original languageEnglish (US)
Pages (from-to)1425-1432
Number of pages8
JournalCurrent Oncology Reports
Volume24
Issue number11
DOIs
StatePublished - Nov 2022

Keywords

  • Immunotherapy
  • Lymphadenectomy
  • Margins
  • Melanoma
  • Neoadjuvant immunotherapy
  • Surgical oncology

ASJC Scopus subject areas

  • Oncology

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