Surgical materials: Current challenges and nano-enabled solutions

Nasim Annabi, Ali Tamayol, Su Ryon Shin, Amir M. Ghaemmaghami, Nicholas A. Peppas, Ali Khademhosseini

Research output: Contribution to journalReview articlepeer-review

160 Scopus citations


Surgical adhesive biomaterials have emerged as substitutes to sutures and staples in many clinical applications. Nano-enabled materials containing nanoparticles or having a distinct nanotopography have been utilized for generation of a new class of surgical materials with enhanced functionality. In this review, the state of the art in the development of conventional surgical adhesive biomaterials is critically reviewed and their shortcomings are outlined. Recent advancements in generation of nano-enabled surgical materials with their potential future applications are discussed. This review will open new avenues for the innovative development of the next generation of tissue adhesives, hemostats, and sealants with enhanced functionality for various surgical applications.

Original languageEnglish (US)
Pages (from-to)574-589
Number of pages16
JournalNano Today
Issue number5
StatePublished - Nov 1 2014
Externally publishedYes


  • Antibacterial bioadhesives
  • Hemostatic agents
  • Nano-enabled surgical materials
  • Sealants
  • Tissue adhesives

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering
  • Biomedical Engineering
  • General Materials Science
  • Pharmaceutical Science


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