Surgical treatment of thymoma

Quintessa Miller, Michael J. Moulton, Jerry Pratt

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Purpose: A case report is presented of a 66-year-old white woman with a 3-month history of atypical chest pain and shortness of breath. Methods: A lateral chest radiograph demonstrated an anterior mediastinal density. A subsequent computed comography (CT) scan revealed a mass in the right anterolateral mediastinum. Fine-needle aspiration (FNA) revealed tumor cells positive for cytokeratin and negative for leukocyte common antigen. Results: The differential diagnosis at that time included thymoma versus thymic carcinoid. She underwent a median sternotomy with complete thymectomy. The pathology revealed a large thymoma with microinvasion into the surrounding adipose tissue. She had an uneventful postoperative course and later underwent adjuvant radiation therapy. Conclusions: Surgical treatment of thymoma is discussed, with emphasis on diagnosis and treatment. Although some patients may present with symptoms caused by involvement of surrounding structures, most thymomas are discovered incidentally on chest radiograph. Various diagnostic procedures can aid the surgeon in ruling out other neoplasms, such as lymphoma or germ cell tumors. Prognosis is not based on histology, but on the tumor's gross characteristics at operation. Benign tumors are noninvasive and encapsulated. All patients with potentially resectable lesions should undergo en-bloc excision. Radiation or chemotherapy should be instituted in more advanced tumors. (

Original languageEnglish (US)
Pages (from-to)101-105
Number of pages5
JournalCurrent surgery
Volume59
Issue number1
DOIs
StatePublished - 2002

Keywords

  • Mediastinal mass
  • Thymectomy
  • Thymoma
  • Thymus

ASJC Scopus subject areas

  • Surgery

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