Abstract
Abstract Deuteriu-labeling studies carried out in conjunction with investigations into the directed catalytic asymmetric hydroboration of unsaturated oxime ethers reveal a surprisingly facile ortho-metallation or σ-bond metathesis pathway that diverts the expected course of CAHB to a tandem C-H activation/hydroboration reaction pathway.
Original language | English (US) |
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Article number | 45600 |
Pages (from-to) | 3306-3310 |
Number of pages | 5 |
Journal | Tetrahedron Letters |
Volume | 56 |
Issue number | 23 |
DOIs | |
State | Published - Dec 1 2015 |
Keywords
- C-H activation
- Directed metallation
- Rhodium-catalyzed borylation
- Rhodium-catalyzed hydroboration
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry