@article{33c969db8c084494a632b0dbc744cf64,
title = "Surprisingly facile C-H activation in the course of oxime-directed catalytic asymmetric hydroboration",
abstract = "Abstract Deuteriu-labeling studies carried out in conjunction with investigations into the directed catalytic asymmetric hydroboration of unsaturated oxime ethers reveal a surprisingly facile ortho-metallation or σ-bond metathesis pathway that diverts the expected course of CAHB to a tandem C-H activation/hydroboration reaction pathway.",
keywords = "C-H activation, Directed metallation, Rhodium-catalyzed borylation, Rhodium-catalyzed hydroboration",
author = "Thacker, {Nathan C.} and Shoba, {Veronika M.} and Geis, {Andrew E.} and Takacs, {James M.}",
note = "Funding Information: We gratefully acknowledge financial support for these studies from the NIH ( GM100101 ) and from the NSF ( CHE-0091975 , MRI-0079750 ) and NIH ( SIG-1-510-RR-06307 ) for the NMR spectrometers used in these studies carried out in facilities renovated under NIH RR016544. We thank M.P. Takacs for carrying out some early experiments synthesizing the oxime ether substrates and S.M. Smith for some early exploratory investigations into the CAHB of oxime ether substrates. Publisher Copyright: {\textcopyright} 2014 Elsevier Ltd.",
year = "2015",
month = dec,
day = "1",
doi = "10.1016/j.tetlet.2014.12.076",
language = "English (US)",
volume = "56",
pages = "3306--3310",
journal = "Tetrahedron Letters",
issn = "0040-4039",
publisher = "Elsevier Limited",
number = "23",
}