Survival Outcome of Sepsis in Recipients of Solid Organ Transplant

Research output: Contribution to journalArticlepeer-review

Abstract

Sepsis is a complex disease stemming from a dysregulated immune response toward an infectious agent. In transplantation, sepsis remains one of the leading causes of morbidity and mortality. Solid organ transplant recipients have impaired adaptive immunity due to immunosuppression required to prevent rejection. Immunosuppression has unintended consequences, such as increasing the risk of infections and sepsis. Due to its high morbidity and mortality, early detection of sepsis is paramount to start aggressive treatment. Several biomarkers or combination of biomarkers of sepsis have emerged in the last decade, but they are not dependable for early diagnosis or for outcome prognosis.

Original languageEnglish (US)
Pages (from-to)717-725
Number of pages9
JournalSeminars in Respiratory and Critical Care Medicine
Volume42
Issue number5
DOIs
StatePublished - Oct 1 2021

Keywords

  • outcome
  • sepsis
  • solid organ transplant
  • survival

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Critical Care and Intensive Care Medicine

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