TY - JOUR
T1 - Sustained ventricular tachycardia after repair of tetralogy of Fallot
T2 - New electrophysiologic findings
AU - Kugler, John D.
AU - Pinsky, William W.
AU - Cheatham, John P.
AU - Hofschire, Philip J.
AU - Mooring, Paul K.
AU - Fleming, William H.
PY - 1983/4
Y1 - 1983/4
N2 - Ventricular arrhythmia originating from the outflow tract of the right ventricle is a presumed cause of late sudden death in patients after repair of tetralogy of Fallot. Exercise testing has been shown to enhance detection, and phenytoin has been shown to control ventricular arrhythmias in these patients. This study reports new findings in 3 patients who underwent electrophysiologic studies at postoperative cardiac catheterization; in each, sustained ventricular tachycardia was induced and found to originate from the inflow-septal area of the right ventricle. Using serial studies, the same sustained ventricular tachycardia was induced during therapeutic serum concentrations of phenytoin but not after propranolol. No patient had ventricular arrhythmia during a 24-hour electrocardiogram or during exercise. Although no patient had normal hemodynamic function, only 1 patient had right ventricular pressure greater than two-thirds systemic pressure. Each patient had undergone initial intracardiac repair at a relatively late age (3, 9, and 9 years).
AB - Ventricular arrhythmia originating from the outflow tract of the right ventricle is a presumed cause of late sudden death in patients after repair of tetralogy of Fallot. Exercise testing has been shown to enhance detection, and phenytoin has been shown to control ventricular arrhythmias in these patients. This study reports new findings in 3 patients who underwent electrophysiologic studies at postoperative cardiac catheterization; in each, sustained ventricular tachycardia was induced and found to originate from the inflow-septal area of the right ventricle. Using serial studies, the same sustained ventricular tachycardia was induced during therapeutic serum concentrations of phenytoin but not after propranolol. No patient had ventricular arrhythmia during a 24-hour electrocardiogram or during exercise. Although no patient had normal hemodynamic function, only 1 patient had right ventricular pressure greater than two-thirds systemic pressure. Each patient had undergone initial intracardiac repair at a relatively late age (3, 9, and 9 years).
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U2 - 10.1016/0002-9149(83)90359-4
DO - 10.1016/0002-9149(83)90359-4
M3 - Article
C2 - 6837460
AN - SCOPUS:0020658251
SN - 0002-9149
VL - 51
SP - 1137
EP - 1143
JO - The American Journal of Cardiology
JF - The American Journal of Cardiology
IS - 7
ER -