Synbiotics for Improved Human Health: Recent Developments, Challenges, and Opportunities

Janina A. Krumbeck, Jens Walter, Robert W. Hutkins

Research output: Contribution to journalReview articlepeer-review

19 Scopus citations


Research on combining pro- and prebiotics as synbiotics to enhance human and animal health has accelerated in the past 10 years, including many clinical trials that have assessed a diverse range of synbiotic formulations. In this review, we summarize these studies as well as the commercial applications of synbiotics that are available. In particular, we critically assess the claimed health benefits of synbiotic applications and the ecological and therapeutic factors to consider when designing synbiotics and discuss the implications of these concepts for future research in this field.

Original languageEnglish (US)
Pages (from-to)451-479
Number of pages29
JournalAnnual Review of Food Science and Technology
StatePublished - Mar 25 2018


  • Gut health
  • Prebiotics
  • Probiotics
  • Synbiotics

ASJC Scopus subject areas

  • Food Science


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