Synthesis and reduction kinetics of sterically shielded pyrrolidine nitroxides

Joseph T. Paletta, Maren Pink, Bridget Foley, Suchada Rajca, Andrzej Rajca

Research output: Contribution to journalArticle

72 Scopus citations

Abstract

A series of sterically shielded pyrrolidine nitroxides were synthesized, and their reduction by ascorbate (vitamin C) indicate that nitroxide 3, a tetraethyl derivative of 3-carboxy-PROXYL, is reduced at the slowest rate among known nitroxides, i.e., at a 60-fold slower rate than that for 3-carboxy-PROXYL.

Original languageEnglish (US)
Pages (from-to)5322-5325
Number of pages4
JournalOrganic Letters
Volume14
Issue number20
DOIs
StatePublished - Oct 19 2012

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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