TY - JOUR
T1 - Synthesis, characterization, and antitumor activity of 5-iodouracil complexes
AU - Singh, Udai P.
AU - Singh, Badri N.
AU - Ghose, Animesh K.
AU - Singh, Rakesh K.
AU - Sodhi, Ajit
PY - 1991/12
Y1 - 1991/12
N2 - Complexes of 5-iodouracil (5IU) with Mn(II), Co(II), Cu(II), Zn(II), and Cd(II) ions have been prepared, characterized, and subjected to a screening system for evaluation of antitumor activity against Sarcoma-180 (S-180) and L 929 tumor cells. The complexes were characterized by their elemental analysis, infrared spectra, electronic spectra, magnetic measurements, and powder x-ray diffraction. The antitumor activity results indicate that some complexes have good antitumor activity both in vivo and in vitro against S-180 and L 929 tumor cells.
AB - Complexes of 5-iodouracil (5IU) with Mn(II), Co(II), Cu(II), Zn(II), and Cd(II) ions have been prepared, characterized, and subjected to a screening system for evaluation of antitumor activity against Sarcoma-180 (S-180) and L 929 tumor cells. The complexes were characterized by their elemental analysis, infrared spectra, electronic spectra, magnetic measurements, and powder x-ray diffraction. The antitumor activity results indicate that some complexes have good antitumor activity both in vivo and in vitro against S-180 and L 929 tumor cells.
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U2 - 10.1016/0162-0134(91)84033-6
DO - 10.1016/0162-0134(91)84033-6
M3 - Article
C2 - 1662711
AN - SCOPUS:0026347490
SN - 0162-0134
VL - 44
SP - 277
EP - 282
JO - Journal of Inorganic Biochemistry
JF - Journal of Inorganic Biochemistry
IS - 4
ER -